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Кашкалда, Д. А.; Kosovtsova, G. V.; Турчина, С. І.; Sukhova, L. L.; Sotnikova–Meleshkina, Zh. V.

doi:10.21856/j-pep.2020.1.04

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…An important role in the period of sexual development, which coincides with the middle school age, is played by thyroid hormones, which are involved in metabolic processes, bone and skeletal formation, growth process, development of sexual characteristics [16,17].…”

Section: Discussionmentioning

confidence: 99%

“…At the same time, growth retardation was registered in almost 10% of boys, sexual dysfunction in every sixth adolescent boy, which was twice as common as among girls of the same age group. Previous studies have shown that oxidative stress caused by an imbalance of thyroid hormones in hypothyroidism affects testosterone levels and, consequently, the formation of hypoandrogenism in boys [1,8,16,24]. There is a direct correlation between the content of thyroid hormones and nutritional status, fat content in the body [4].…”

Section: Discussionmentioning

confidence: 99%

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The structure of morbidity of secondary school children

Sotnikova–Meleshkina

2020

Rep. of Morph.

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Intensification of the educational process is one of the risk factors for increasing the prevalence of morphofunctional disorders, acute and chronic somatic morbidity, mental and behavioral disorders, maladaptation syndrome. Many researchers have found a negative chronological dynamics of school health and a high incidence among secondary school students. The purpose of the study is a comparative analysis of the structure and dynamics of morbidity of children during secondary school. The study involved more than 266 students of secondary schools aged 10 to 14 years. The state of health was assessed according to preventive medical examinations conducted by specialists of the Institute of Child and Adolescent Health of the National Academy of Medical Sciences of Ukraine with the informed consent of parents and according to the bioethical norms of the Helsinki Declaration (as amended in 2013). Statistical data processing was performed using the licensed package SPSS Statistic v.20 using Student’s t test. The highest level of morbidity was found in diseases of the endocrine system (468.4±39.7‰), the organ of vision and the appendix (322.8±37.2‰), the circulatory system (310.1±36.8‰) and respiration (303.8±36.6‰). Among girls, endocrine (520.7±57.7‰) and ophthalmological pathology (386.7±56.2‰) were more often registered, and among boys – mental and behavioral disorders (168.7±39.9‰; p<0.05). During the training, negative dynamics was determined for diseases of the endocrine system (due to a probable increase in their number among boys, at p<0.05), diseases of the digestive system, eye and appendages due to decreased visual acuity (p<0.01). In the structure of endocrine pathology, 60% were thyroid diseases in both sexes, and the prevalence of grade 1 obesity was higher among boys (p<0.05). Mental and behavioral disorders were mainly represented by disorders of activity and attention in adolescent boys, sleep disorders – in girls; hyperkinetic behavioral disorders – in both sex groups. Gender features in the structure and dynamics of morbidity of secondary school students to a greater extent in diseases of the endocrine system, eye and appendix with a general negative tendency to increase the prevalence of these groups of diseases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The structure of morbidity of secondary school children

Sotnikova–Meleshkina

2020

Rep. of Morph.

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Biological and medical value of antioxidant protection system of the human body

Kovalyova

Pasiieshvili

2021

MTT

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The article is devoted to the antioxidant system of the human body in the context of biological and medical significance. The classification of antioxidants in terms of their physical and chemical properties, bioorganic compounds, biochemical effects, mechanisms of implementation of antioxidant protection is presented. The given processes of extreme radical oxidation and mechanisms of antioxidant defense in physiological and pathological conditions. The characteristics of the components of the glutathione system, namely glutathione and enzymes – glutathione peroxidase, glutathione reductase and glutathione transferase are presented. Much attention is paid to manganese superoxide dismutase, an antiradical defense enzyme, as a fundamental regulator of cell proliferation, a mediator of metabolism and apoptosis. Interpretation of changes in the antioxidant enzyme of mitochondrial origin from a prognostic point of view is interpreted on the basis of the results of clinical observations carried out by scientists in various human diseases. The expediency of determining manganese superoxide dismutase in clinical practice for the diagnostic search for the direction of the pathological process, the timely detection of complications and the appointment of adequate therapy is emphasized. Keywords: antioxidant system, classification, glutathione system, manganese superoxide dismutase.

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Historical aspects of development of the Kharkiv school of food hygiene and nutritiology (stages, trends and prospects)

Podrіgalo

Sotnikova–Meleshkina

2021

MTT

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Analyzed in this article are historical aspects of the Kharkiv school of food hygiene and nutritiology from its inception to the present. Key stages of development are identified, including university stage (since the opening of the Department of Hygiene at the Kharkiv Imperial University in 1873 under the leadership of Professor A.I. Iakobii), department stage (since the early 1930s under the leadership of Associate Professor M.Z. Lukyanovich, Professor V.O. Sivoronov, Associate Professor M.I. Ivashchenko, and since 1983 – Professor M.V. Krivonosov), as well as interuniversity stage (since the beginning of the 21st century to the present, with the involvement of specialists not only from various universities of Kharkiv, but also scientists from other cities). Principal directions of the department stage of the period are assessment of actual nutrition, developing rationale for focus of a diet, limiting imbalanced peroxidation of lipids with food antioxidants, alimentary prevention and rehabilitation of pre-nosological conditions, increasing potential of adaptive capabilities of children affected by the Chernobyl disaster, the issue of phytoadaptogens, the development of nutritiology, the concept of "alimentary-related pre-nosology", the issue of health and nutrition monitoring, developing rationale for focus of nutrition of athletes in strength sports, studying the eating behavior of students. The interuniversity stage demonstrates continuity of all periods of development of the scientific school and is characterized by the active use of alimentary methods in health monitoring, the introduction of principles of sport nutritiology stemming from studies of the Professor M.V. Krivonosov. Activity of specialists during the existence of the school is analyzed and key scientific achievements and publications in professional journals and scientometric publications are covered. Keywords: nutritiology, food hygiene, history of development.

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Cited by 3 publications

References 5 publications

The structure of morbidity of secondary school children

The structure of morbidity of secondary school children

Biological and medical value of antioxidant protection system of the human body

Historical aspects of development of the Kharkiv school of food hygiene and nutritiology (stages, trends and prospects)

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