WITHDRAWN: Assessment of DOK7 and SPDEF as Potential Epigenetic Biomarkers in Whole Blood of Patients with Gastric Adenocarcinoma and Intestinal Metaplasia
Abstract:BackgroundGastric cancer (GC) is the fifth most prevalent cancer, and intestinal metaplasia (IM) is generally considered a precancerous lesion in the gastric carcinogenesis cascade. DNA methylation is one of the most deeply studied epigenetic modifications. Numerous studies have been shown that aberrant methylation of DOK7, an adaptor protein, and SPDEF, a transcription factor, correlates with carcinogenesis. This study aimed to investigate DNA methylation of DOK7 and SPDEF in the whole blood specimens obtaine… Show more
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