Wise use of perioperative antibiotics

Abstract

NOSOCOMIAL SURGICAL SITE INFECTIONS (SSIs), especially those caused by antibiotic-resistant organisms, are a major concern for perioperative nurses. Administering the correct antibiotic at its effective dose within the optimal time frame can help prevent SSIs. THE SIGNIFICANT RELATIONSHIP between microbial resistance and overuse of antibiotics justifies an examination of practices and a move away from widespread antibiotic administration. NEW ANTIBIOTIC GUIDELINES and research support recommendations for antibiotic administration for specific cardiac, colorectal, gynecologic, ophthalmologic, orthopedic, and urinary surgical procedures. Perioperative nurses can help protect their patients from nosocomial SSIs by using this clinical evidence.

Enterobacter Bacteremia: Clinical Features, Risk Factors for Multiresistance and Mortality in a Chinese University Hospital

“…In multivariate analysis, previous third-generation cephalosporins therapy and prolonged perioperative prophyiaxis were strong independent predictors for multiresistance in patients with Enterobacter bacteremia. This is consistent with the results of other studies on Enterobacter species [12,13]. Such high rates of multiresistance have been attributed to the wide, injudicious, and uncontrolled antibiotic use, especially with third-generation cephalosporins use in hospitals and other nonmedical areas.…”