Wirkung und Verhalten von Veronal und Luminal bei chronischer Zufuhr

Krautwald, A; Oettel, H.

doi:10.1007/bf01929685

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Microchemical Equipment1

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1938

1975

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Cited by 10 publications

(2 citation statements)

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“…The melting point (determinedon the microapparatus) of the sublimate from the weighed product and the crystallographic properties of the crystals (11,13) proved to be that of the barbituric acid in question. This method is also applicable in cases of identification of barbiturates in biologic liquids like urine and spinal fluid (14,18,28,29).…”

Section: Microchemical Equipmentmentioning

confidence: 99%

The Microchemical Laboratory of the American Medical Association

Peterson¹,

Schoeffel²

1938

Ind. Eng. Chem. Anal. Ed.

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Section: Microchemical Equipmentmentioning

confidence: 99%

The Microchemical Laboratory of the American Medical Association

Peterson¹,

Schoeffel²

1938

Ind. Eng. Chem. Anal. Ed.

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“…This variation in duration of response may be due to fluctuations in the rate of destruction of the drug. Krautwald and Oettel [1937] and Krautwald [1937] measured the daily excretion of barbitone, phenobarbitone, and phanodorm and noctal given to dogs in constant daily doses over prolonged periods. Their protocols show very considerable daily fluctuations in the amounts of drugs excreted, a fact which suggests a considerable fluctuation in the amount of drug daily destroyed in the body.…”

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confidence: 99%

Dynamic Variation in Response to Barbiturates

Clark

Raventós

1940

Exp Physiol

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1. There is a fairly high individual constancy as regards sensitivity to barbiturates; individuals which are narcosised by a median hypnotic dose are likely to show the same response when the test is repeated. 2. There is less individual constancy as regards the duration of narcosis produced by barbiturates. Such constancy can be demonstrated in groups of mice selected as regards sensitivity, but in unselected groups we could not demonstrate any constancy. The expenses of this research were defrayed by a grant from Messrs. Imperial Chemical Industries (Dyestuffs Group), for which the authors express their thanks. We also thank Dr. W. O. Kermack for his kind assistance in the mathematical analysis of the results.

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Forensische Toxikologie

Mueller

1953

Gerichtliche Medizin

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Wirkung und Verhalten von Veronal und Luminal bei chronischer Zufuhr

Cited by 10 publications

References 10 publications

The Microchemical Laboratory of the American Medical Association

The Microchemical Laboratory of the American Medical Association

Dynamic Variation in Response to Barbiturates

Forensische Toxikologie

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