Wilms tumor with extensive cardiac thrombus: a multidisciplinary approach

Abstract

Wilms tumor is the second most common intraabdominal malignancy in childhood. Vessel invasion with thrombus formation is a well-known phenomenon in Wilms tumor and is found in 30% of these children. This report describes a 4-year-old boy with a left kidney Wilms tumor and extensive thrombi formation with intracardiac extension. He underwent a left radical nephrectomy under cardiopulmonary bypass following a single dose of chemotherapy. Emergency surgery with cardiopulmonary bypass may be lifesaving in children with cardiac compromise in the presence of extensive thrombosis.

Impact of neoadjuvant chemotherapy on thrombus viability in patients with Wilms tumour and caval extension: systematic review with meta-analysis

“…Thrombectomy is undertaken for oncological control to achieve a complete resection, but may be required urgently to prevent complications from its haemodynamic effects, including tumour embolus and hepatic and cardiac failure 13–16 .…”