Abstract:Myopia has become the major cause of visual impairment
worldwide.
Although the pathogenesis of myopia remains controversial, proteomic
studies suggest that dysregulation of retinal metabolism is potentially
involved in the pathology of myopia. Lysine acetylation of proteins
plays a key role in regulating cellular metabolism, but little is
known about its role in the form-deprived myopic retina. Hence, a
comprehensive analysis of proteomic and acetylomic changes in the
retinas of guinea pigs with form-deprivati… Show more
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