Wide-scope target screening of >2000 emerging contaminants in wastewater samples with UPLC-Q-ToF-HRMS/MS and smart evaluation of its performance through the validation of 195 selected representative analytes

Influence of Emission Sources and Tributaries on the Spatial and Temporal Patterns of Micropollutant Mixtures and Associated Effects in a Small River

“…Chemical analysis and in vitro bioassays are complementary screening approaches which capture a broad range of organic micropollutants and have previously been used to assess the quality of treated and untreated wastewater and their impact on river water quality (Farré and Barceló 2003;König et al 2017;Neale et al 2017b) or to track pesticides in surface water from agricultural areas (Lundqvist et al 2019). Whereas chemical analysis provides information on the identity and quantity of individual micropollutants (Gago-Ferrero et al 2019), in vitro bioassays give information on the combined effect of all bioactive compounds present in a sample and on their mode of action (Neale et al 2017b;Müller et al 2019). In the present study a battery of 4 in vitro bioassays was applied that covered the environmentally relevant modes of action, aryl hydrocarbon receptor induction (Brennan et al 2015), peroxisome proliferator-activated receptor activity (Neale et al 2017a), estrogenicity (König et al 2017), and oxidative stress response (Escher et al 2012(Escher et al , 2013b.…”

A critical review on environmental presence of pharmaceutical drugs tested for the covid-19 treatment

“… Ibáñez et al (2017) performed analyzes of wastewater samples treated at the WWTP in Athens, Greece in October 2014 for seven consecutive days and detected the chemical Atazanavir in six of the samples analyzed. The authors Gago-Ferrero et al (2020) conducted their studies at the same WWTP in Athens, were able to quantify Atazanavir (0.02 µg L -1 ), Darunavir (0.15 µg L -1 ) and Emtricitabine (0.33 µg L -1 ) at intake water.…”

Smart Adsorbents for Aquatic Environmental Remediation

“…adsorption/desorption cycles. [151] Polyethylenimine (PEI)/ethyl cellulose (EC) composite was used as a pH-response adsorbent for removal of Cr 6+ with a wide pH range (3)(4)(5)(6)(7)(8)(9)(10)(11). It was reported that 4.0 mg L −1 of Cr 6+ from 20 mL solution was completely removed by 60 mg polyethylenimine/ethyl cellulose composite dose within a 5 min contact time under acidic conditions (pH 3).…”

“…The penetration and persistence of anthropogenic metals ions [1,2] and organic xenobiotics [3][4][5][6][7][8][9][10][11][12] into the natural waters continue to remain severe environmental health and ecosystem-related issues. Cytotoxic pollutants have long-lasting noxious metabolic effects on living organisms, [13,14] eventually leading to toxicity, [15,16] and mortality.…”