Wide-Field Spectral Domain Optical Coherence Tomography

Pichi, Francesco; Carrai, Paola; Bonsignore, Francesco; Ciardella, Antonio P.; Nucci, Paolo

doi:10.1097/iae.0000000000000611

Cited by 16 publications

(9 citation statements)

References 32 publications

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“…Pichi et al published a similar study as Carrai et al examining eyes with wet age-related macular degeneration, dry age-related macular degeneration, retinitis pigmentosa, adult exudative polymorphous dystrophy and central serous chorioretinopathy. 15 In their study a montage approach was also used to produce a single wide-field SD-OCT image reported as spanning “entire posterior pole spanning ∼200° horizontally and vertically, from equator to equator”, but which did not include the far periphery, as in our images (Figure 3 and Supplemental Figure 12, available at http://aaojournal.org). Finally, Uji and Yoshimura published on ten normal patients using swept source-OCT images that spanned 70° of the retina, in an approach they termed as “extended field imaging.” 16 While these prior studies exclusively used a montaged approach to image the retina periphery, except Uji & Yoshimura, whose images were limited to 70°, our study demonstrates a novel technique to image the far retinal periphery using a 30° steerable lens.…”

Section: Discussionmentioning

confidence: 99%

Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery

et al. 2016

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Objective To describe the spectral-domain optical coherence tomography (SD-OCT) features of peripheral retinal findings using an ultra-widefield (UWF) steering technique to image the retinal periphery. Design Observational study. Participants 68 patients (68 eyes) with 19 peripheral retinal features. Main Outcome Measures SD-OCT-based structural features. Methods Nineteen peripheral retinal features including: vortex vein, congenital hypertrophy of the retinal pigment epithelium (CHRPE), pars plana, ora serrata pearl, typical cystoid degeneration (TCD), cystic retinal tuft, meridional fold, lattice and cobblestone degeneration, retinal hole, retinal tear, rhegmatogenous retinal detachment (RRD), typical degenerative senile retinoschisis, peripheral laser coagulation scars, ora tooth, cryopexy scars (retinal tear and treated retinoblastoma scar), bone spicules, white without pressure, and peripheral drusen were identified by peripheral clinical examination. Near infrared (NIR) scanning laser ophthalmoscopy (SLO) images and SD-OCT of these entities were registered to UWF color photographs. Results SD-OCT resolved structural features of all peripheral findings. Dilated hyporeflective tubular structures within the choroid were observed in the vortex vein. Loss of retinal lamination, neural retinal attenuation, RPE loss or hypertrophy were seen in several entities including CHRPE, ora serrata pearl, TCD, cystic retinal tuft, meridional fold, lattice and cobblestone degenerations. Hyporeflective intraretinal spaces, indicating cystoid or schitic fluid, were seen in ora serrata pearl, ora tooth, TCD, cystic retinal tuft, meridional fold, retinal hole, and typical degenerative senile retinoschisis. The vitreoretinal interface, which often consisted of lamellae-like structures of the condensed cortical vitreous near or adherent to the neural retina, appeared clearly in most peripheral findings, confirming its association with many low-risk and vision-threatening pathologies such as lattice degeneration, meridional folds, retinal breaks, and RRDs. Conclusions UWF steering technique-based SD-OCT imaging of the retinal periphery is feasible with current commercially available devices, and provides detailed anatomical information of the peripheral retina, including benign and pathological entities, not previously imaged. This imaging technique may deepen our structural understanding of these entities, their potentially associated macular and systemic pathologies, and may influence decision-making in clinical practice, particularly in areas with teleretinal capabilities but poor access to retinal specialists.

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Section: Discussionmentioning

confidence: 99%

Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery

et al. 2016

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“…Although this clinical presentation is rarely reported in literature, the administration of steroid in such cases has never been reported. [ 3 4 ] In our case, the increasing in intraretinal cysts was accompanied by visual acuity decay. Therefore, we decided to treat the patient with steroid on an empirical basis.…”

Section: Discussionmentioning

confidence: 50%

Acute exudative polymorphous vitelliform maculopathy: To bolus or not to bolus?

2018

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Acute exudative polymorphous vitelliform maculopathy (AEPVM) is a rare bilateral maculopathy characterized by chronic and long-term course. We report a case of AEPVM with an unusual presentation and management in a middle-aged man. He presented with clinical features of bilateral AEPVM accompanied by multiple intraretinal cysts, with a sudden increase of intraretinal fluid and visual function deterioration over a span of few days. Therefore, we administered empirically an intravenous bolus injection of methylprednisolone. One week after, there was a full recovery of visual acuity and cystic intraretinal spaces completely disappeared.

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“…Correct assessment of the VMI is of particular interest, given that the configuration impacts the treatment response and treatment need in DME, but also in exudative age-related macular degeneration and CME due to uveitis or retinal vein occlusions [17,21,22] . Wide-field OCT studies showed that the vitreous interface can be clearly delineated using this imaging technique [8,10,19] . These findings emphasize the critical role of the correct assessment of the vitreous cortex in respective diseases, which may be facilitated using wide-field SD-OCT.…”

Section: Discussionmentioning

confidence: 99%

“…Wide-field OCT is a new method and of great interest especially when both the periphery as well as the posterior pole need to be assessed in a single scan [11] . So far, widefield and ultra-wide-field OCT were used in order to describe the peripheral retinochoroid morphology and peripheral changes associated with retinitis pigmentosa, choroidal nevi, choroidal melanomas, acute exudative polymorphous vitelliform maculopathy, macular holes, and congenital X-linked retinoschisis [6,8,10,11,19,20] . This is the first study to compare conventional 30° with 55° wide-field SD-OCT using a predefined scanning pattern and grading protocol in order to assess whether widefield SD-OCT may also offer potential benefit in diseases mainly confined to the macular area, and whether it may allow a more precise detection of morphological features outside conventional 30° OCT. We found a strong agreement between both image modalities for morphological features such as IRF, SRF, HE, CWS, and MA.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of 55° Wide-Field Spectral Domain Optical Coherence Tomography and Conventional 30° Optical Coherence Tomography for the Assessment of Diabetic Macular Edema

Munk

Lincke

Giannakaki-Zimmermann

et al. 2017

Ophthalmologica

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Purpose: To compare conventional 30° spectral domain optical coherence tomography (SD-OCT) with 55° wide-field SD-OCT for the assessment of diabetic macular edema (DME). Methods: This study included 50 DME patients. Both 55° and 30° SD-OCT was conducted. Two readers evaluated scans according to a standardized grading protocol. Intergrader agreement as well as agreement between 30° and 55° SD-OCT were assessed. Results: Intergrader agreement (κ) was strong and ranged from 0.79 to 1.0. Perfect interdevice agreement (κ = 1.0) was found for the detection of intra- and subretinal fluid. Excellent agreement (κ ≥ 0.9) was found for the presence of epiretinal membrane (κ = 0.92) and cotton-wool spots (κ = 0.92). A strong agreement was found for the presence of hard exudates (κ = 0.89) and microaneurysms (κ = 0.81). A moderate correlation was found for ellipsoid zone integrity (κ = 0.69) and configuration of the vitreomacular interface (VMI) (κ = 0.69). A weak agreement was found for retinal pigment epithelium atrophy (κ = 0.51) and external limiting membrane integrity (κ = 0.35). Conclusion: Wide-field OCT imaging may be beneficial for evaluating DME, particularly for assessing the VMI and the integrity of hyperreflective bands.

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Wide-Field Spectral Domain Optical Coherence Tomography

Cited by 16 publications

References 32 publications

Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery

Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery

Acute exudative polymorphous vitelliform maculopathy: To bolus or not to bolus?

Comparison of 55° Wide-Field Spectral Domain Optical Coherence Tomography and Conventional 30° Optical Coherence Tomography for the Assessment of Diabetic Macular Edema

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