American middle cities (those between 50,000 and 1 million residents) are home to a quarter of all Americans and are on the frontlines of climate change, yet they are largely excluded from the literature on urban climate politics. At the same time, while the literature highlights the importance of state institutions, state capacity, and environmental coalitions, less is known about how these factors interact with local political and economic conditions. I advance the field by directly considering these local contextual features through original ethnographic fieldwork in four middle cities. I find that the composition of coalitions both for and against climate policies can differ widely based on a city’s economic base and racial homogeneity. In addition, analysis of these middle cities demonstrates a challenge in overcoming the physical legacy of industrialization. Taken together, this paper sheds new light on urban environmental politics by focusing on a category of understudied cities that house a large section of the country’s population and economic output, while also being home to some of its most economically and environmentally disadvantaged communities.