Why Is a b-value Range of 1500–2000 s/mm<sup>2</sup> Optimal for Evaluating Prostatic Index Lesions on Synthetic Diffusion-Weighted Imaging?

Yeon, So; Kim, EunJu; Park, Sung Yoon

doi:10.3348/kjr.2020.0836

Cited by 8 publications

(6 citation statements)

References 19 publications

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“…34 Finally, quantitative diffusion MRI enables "computed" diffusion MRI, that is, synthesizing arbitrary high b-values beyond those acquired, with several promising applications. [35][36][37]…”

Section: Potential For Improved Value Through Quantificationmentioning

confidence: 99%

“…Indeed, by removing intra‐ and inter‐reader variability in image interpretation, quantitative diffusion MRI (similarly to other quantitative imaging methods) may provide added value in basic and clinical research (e.g., clinical trials with improved power due to reduced measurement variability), 33 as well as clinical care 34 . Finally, quantitative diffusion MRI enables “computed” diffusion MRI, that is, synthesizing arbitrary high b ‐values beyond those acquired, with several promising applications 35–37 …”

Section: Quantitative Diffusion Mrimentioning

confidence: 99%

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Quantitative diffusion MRI of the abdomen and pelvis

2021

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Diffusion MRI has enormous potential and utility in the evaluation of various abdominal and pelvic disease processes including cancer and noncancer imaging of the liver, prostate, and other organs. Quantitative diffusion MRI is based on acquisitions with multiple diffusion encodings followed by quantitative mapping of diffusion parameters that are sensitive to tissue microstructure. Compared to qualitative diffusion‐weighted MRI, quantitative diffusion MRI can improve standardization of tissue characterization as needed for disease detection, staging, and treatment monitoring. However, similar to many other quantitative MRI methods, diffusion MRI faces multiple challenges including acquisition artifacts, signal modeling limitations, and biological variability. In abdominal and pelvic diffusion MRI, technical acquisition challenges include physiologic motion (respiratory, peristaltic, and pulsatile), image distortions, and low signal‐to‐noise ratio. If unaddressed, these challenges lead to poor technical performance (bias and precision) and clinical outcomes of quantitative diffusion MRI. Emerging and novel technical developments seek to address these challenges and may enable reliable quantitative diffusion MRI of the abdomen and pelvis. Through systematic validation in phantoms, volunteers, and patients, including multicenter studies to assess reproducibility, these emerging techniques may finally demonstrate the potential of quantitative diffusion MRI for abdominal and pelvic imaging applications.

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Section: Potential For Improved Value Through Quantificationmentioning

confidence: 99%

Section: Quantitative Diffusion Mrimentioning

confidence: 99%

Quantitative diffusion MRI of the abdomen and pelvis

2021

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“…Theoretically, when signal attenuation arrives into ultra-high b-value region, the sensitivity to smaller spatial scale enhances and enables DWI to explore tissue microstructure on complexity and heterogeneity more powerfully than routine DWI [ 23 ]. In fact, previous studies has showed that UHBV-DWI performed better than traditional DWI in tumor grading [ 16 ] and detection [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Recently, ultra-high b-value DWI (UHBV-DWI) is increasingly explored in relation to the cerebral system [ 15 – 17 ] and prostate cancer [ 18 , 19 ] and has showed considerable potential in tumor grading and detection. In contrast, there is lack of research with respect to the investigation of UHBV-DWI in rectal cancer.…”

Section: Introductionmentioning

confidence: 99%

Ultra-high b-Value DWI in predicting progression risk of locally advanced rectal cancer: a comparative study with routine DWI

Zhang¹,

Xu²,

Zheng³

et al. 2023

Cancer Imaging

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Background The prognosis prediction of locally advanced rectal cancer (LARC) was important to individualized treatment, we aimed to investigate the performance of ultra-high b-value DWI (UHBV-DWI) in progression risk prediction of LARC and compare with routine DWI. Methods This retrospective study collected patients with rectal cancer from 2016 to 2019. Routine DWI (b = 0, 1000 s/mm2) and UHBV-DWI (b = 0, 1700 ~ 3500 s/mm2) were processed with mono-exponential model to generate ADC and ADCuh, respectively. The performance of the ADCuh was compared with ADC in 3-year progression free survival (PFS) assessment using time-dependent ROC and Kaplan-Meier curve. Prognosis model was constructed with ADCuh, ADC and clinicopathologic factors using multivariate COX proportional hazard regression analysis. The prognosis model was assessed with time-dependent ROC, decision curve analysis (DCA) and calibration curve. Results A total of 112 patients with LARC (TNM-stage II-III) were evaluated. ADCuh performed better than ADC for 3-year PFS assessment (AUC = 0.754 and 0.586, respectively). Multivariate COX analysis showed that ADCuh and ADC were independent factors for 3-year PFS (P < 0.05). Prognostic model 3 (TNM-stage + extramural venous invasion (EMVI) + ADCuh) was superior than model 2 (TNM-stage + EMVI + ADC) and model 1 (TNM-stage + EMVI) for 3-year PFS prediction (AUC = 0.805, 0.719 and 0.688, respectively). DCA showed that model 3 had higher net benefit than model 2 and model 1. Calibration curve demonstrated better agreement of model 1 than model 2 and model 1. Conclusions ADCuh from UHBV-DWI performed better than ADC from routine DWI in predicting prognosis of LARC. The model based on combination of ADCuh, TNM-stage and EMVI could help to indicate progression risk before treatment.

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“…In addition, the DCE parameters used varied: the phase number range was 2–90 and the phase duration range was 3–60 seconds. The highest b-values of 800–2000 sec/mm 2 were not consistent with the highest b-values of ≥ 1400 sec/mm 2 [ 1 19 ]. There are several possible explanations for these findings.…”

Section: Discussionmentioning

confidence: 99%

Use of Imaging and Biopsy in Prostate Cancer Diagnosis: A Survey From the Asian Prostate Imaging Working Group

Wang,

Jinzaki,

Tan

et al. 2023

Korean J Radiol

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Objective To elucidate the use of radiological studies, including nuclear medicine, and biopsy for the diagnosis and staging of prostate cancer (PCA) in clinical practice and understand the current status of PCA in Asian countries via an international survey. Materials and Methods The Asian Prostate Imaging Working Group designed a survey questionnaire with four domains focused on prostate magnetic resonance imaging (MRI), other prostate imaging, prostate biopsy, and PCA backgrounds. The questionnaire was sent to 111 members of professional affiliations in Korea, Japan, Singapore, and Taiwan who were representatives of their working hospitals, and their responses were analyzed. Results This survey had a response rate of 97.3% (108/111). The rates of using 3T scanners, antispasmodic agents, laxative drugs, and prostate imaging-reporting and data system reporting for prostate MRI were 21.6%–78.9%, 22.2%–84.2%, 2.3%–26.3%, and 59.5%–100%, respectively. Respondents reported using the highest b-values of 800–2000 sec/mm 2 and fields of view of 9–30 cm. The prostate MRI examinations per month ranged from 1 to 600, and they were most commonly indicated for biopsy-naïve patients suspected of PCA in Japan and Singapore and staging of proven PCA in Korea and Taiwan. The most commonly used radiotracers for prostate positron emission tomography are prostate-specific membrane antigen in Singapore and fluorodeoxyglucose in three other countries. The most common timing for prostate MRI was before biopsy (29.9%). Prostate-targeted biopsies were performed in 63.8% of hospitals, usually by MRI-ultrasound fusion approach. The most common presentation was localized PCA in all four countries, and it was usually treated with radical prostatectomy. Conclusion This survey showed the diverse technical details and the availability of imaging and biopsy in the evaluation of PCA. This suggests the need for an educational program for Asian radiologists to promote standardized evidence-based imaging approaches for the diagnosis and staging of PCA.

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Why Is a b-value Range of 1500–2000 s/mm² Optimal for Evaluating Prostatic Index Lesions on Synthetic Diffusion-Weighted Imaging?

Cited by 8 publications

References 19 publications

Quantitative diffusion MRI of the abdomen and pelvis

Quantitative diffusion MRI of the abdomen and pelvis

Ultra-high b-Value DWI in predicting progression risk of locally advanced rectal cancer: a comparative study with routine DWI

Use of Imaging and Biopsy in Prostate Cancer Diagnosis: A Survey From the Asian Prostate Imaging Working Group

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Why Is a b-value Range of 1500–2000 s/mm2 Optimal for Evaluating Prostatic Index Lesions on Synthetic Diffusion-Weighted Imaging?

Cited by 8 publications

References 19 publications

Quantitative diffusion MRI of the abdomen and pelvis

Quantitative diffusion MRI of the abdomen and pelvis

Ultra-high b-Value DWI in predicting progression risk of locally advanced rectal cancer: a comparative study with routine DWI

Use of Imaging and Biopsy in Prostate Cancer Diagnosis: A Survey From the Asian Prostate Imaging Working Group

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Why Is a b-value Range of 1500–2000 s/mm² Optimal for Evaluating Prostatic Index Lesions on Synthetic Diffusion-Weighted Imaging?