We quantify the behavior of Cu, Ga, Ge, As, Mo, Ag, Cd, In, Sn, Sb, W, Tl, Pb, and Bi during the differentiation of a picritic magma in the Kilauea Iki lava lake, Hawaii, using whole rock and glass differentiation trends, as well as partition coefficients in Cu-rich sulfide blebs and minerals. Such data allow us to constrain the partitioning behavior of these elements between sulfide and silicate melts, as well as the chalcophile element characteristics of the mantle source of the Kilauea lavas. Nearly all of the elements are generally incompatible on a whole-rock scale, with concentrations increasing exponentially below $6 wt% MgO. However, in-situ laser ablation data reveal that Cu, Ag, Bi, Cd, In, Pb, and Sn are chalcophile; As, Ge, Sb, and Tl are weakly chalcophile to lithophile; and Mo, Ga, and W are lithophile. The average D sulfide/silicate melt values are: