Whole-microwave system modeling for brain imaging

Kanfoud, Ibtissam El; Dolean, Victorita; Migliaccio, Claire; Lanteri, Jérôme; Aliferis, Iannis; Pichot, Christian; Tournier, Pierre-Henri; Nataf, Frédéric; Hecht, Frédéric; Semenov, Serguei; Bonazzoli, Marcella; Rapetti, Francesca; Pasquetti, Richard; Buhan, Maya de; Darbas, Marion

doi:10.1109/cama.2015.7428123

Cited by 9 publications

(8 citation statements)

References 2 publications

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“…This design requirement opposes the compact and light-weight requirement of a portable imaging system. Compactness of the sensing antennas is required to enable using more elements in the array for better imaging quality, as well as reducing the mutual-coupling effects between neighbouring antennas303132333435. All the aforementioned demands of the system make the antenna design process challenging.…”

Section: Resultsmentioning

confidence: 99%

“…It takes less than 2 seconds for the multi-slice system to collect data from one scan (Supplementary Table S2), while data acquisition of previous manual and mechanical rotational scanning system requires 1–4 minutes32333435. The time requirement for data acquisition of the multi-slice head imaging system is also lower when compared to other radar based breast cancer detection systems616263.…”

Section: Discussionmentioning

confidence: 99%

“…Unfortunately, time is critical for ICH affected patients123456. Nevertheless, the imaging resolution of radar based imaging system34 (less than 10 mm ) is comparable to the tomography based head imaging system35363839 (5–7 mm ). This resolution is higher when compared to other portable imaging modalities910111213.…”

Section: Discussionmentioning

confidence: 99%

“…Microwave imaging relies on the contrast of the dielectric properties between healthy and unhealthy tissue. Although utilization of microwave frequencies was pioneered for sensing systems for anomaly detection2122232425 and experimental results to identify ICH25 are available in the literature, the imaging of the head interior is demanded to localize ICH position inside the head26272829303132333435363738. Again, for rapid detection of ICH over-simplification of the electromagnetic radiation is noted for the sensing systems, e.g.…”

mentioning

confidence: 99%

“…At the same time, these issues can potentially jeopardise the continuous monitoring of the patient upon initial diagnosis. The reported automated head imaging prototypes353637383940 use complex imaging system infrastructure involving matching liquids and relatively bulky switching network3536373839 in order to improve precision and accelerate data acquisition. However, they are designed for narrow band operation and require huge time (from tens of minutes to hours40 depending on the required imaging accuracy) for image reconstruction, which is often shortened by using a dedicated supercomputer353839.…”

mentioning

confidence: 99%

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On-site Rapid Diagnosis of Intracranial Hematoma using Portable Multi-slice Microwave Imaging System

Mobashsher

Abbosh

2016

Sci Rep

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Rapid, on-the-spot diagnostic and monitoring systems are vital for the survival of patients with intracranial hematoma, as their conditions drastically deteriorate with time. To address the limited accessibility, high costs and static structure of currently used MRI and CT scanners, a portable non-invasive multi-slice microwave imaging system is presented for accurate 3D localization of hematoma inside human head. This diagnostic system provides fast data acquisition and imaging compared to the existing systems by means of a compact array of low-profile, unidirectional antennas with wideband operation. The 3D printed low-cost and portable system can be installed in an ambulance for rapid on-site diagnosis by paramedics. In this paper, the multi-slice head imaging system’s operating principle is numerically analysed and experimentally validated on realistic head phantoms. Quantitative analyses demonstrate that the multi-slice head imaging system is able to generate better quality reconstructed images providing 70% higher average signal to clutter ratio, 25% enhanced maximum signal to clutter ratio and with around 60% hematoma target localization compared to the previous head imaging systems. Nevertheless, numerical and experimental results demonstrate that previous reported 2D imaging systems are vulnerable to localization error, which is overcome in the presented multi-slice 3D imaging system. The non-ionizing system, which uses safe levels of very low microwave power, is also tested on human subjects. Results of realistic phantom and subjects demonstrate the feasibility of the system in future preclinical trials.

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