Whole body and local cryotherapy in restless legs syndrome: A randomized, single-blind, controlled parallel group pilot study

The Effect of the cool dialysate on the restless leg syndrome in hemodialysis patients: Randomized triple-blind clinical trial

“…showed reduction of the local and whole body temperature with cryotherapy has been successful in reducing RLS symptoms. They observed that local cryotherapy was less effective than whole body cooling[23] which is in line with the results of the recent study. Improvement symptoms of RLS by reducing body temperature may be due to decreased function of sensory receptors, leading to a reduction in neuronal activity with extensive anesthesia.…”

Novel Exercises for Restless Legs Syndrome: A Randomized, Controlled Trial

“…Not only are the specific effects of interest in supporting people with this condition, but the impact of group interaction needs to be partitioned in outcomes analysis in future trials of therapies. None of the eleven randomized controlled trials investigating nonpharmacological therapies for RLS [12][13][14][15][16][17][18][19][20][21][22] have provided insight into the potential effects of group therapy on symptoms, so this seems to be an important target for future attention.…”

“…However, high-quality guidelines published by Aurora et al 10 (AGREE assessment "recommended" 11 ) concluded that there was insufficient evidence for nonpharmacological therapy. A recent review by the authors of eleven randomized trials [12][13][14][15][16][17][18][19][20][21][22] concluded that some nonpharmacological interventions including exercise and acupuncture seem beneficial for RLS symptoms; however, few studies were identified and the level of evidence was often not high. Given common unwanted side effects associated with pharmacological management, nonpharmacological treatment options may be valuable for symptom reduction.…”

Qualidade do sono em pacientes insulinodependentes

“…No presente artigo foi possível observar que 16,8% das mulheres apresentam alto risco de desenvolver síndrome das pernas inquietas. Este achado vai de encontro a um estudo realizado em 2016 que documenta esta patologia como sendo mais frequente em indivíduos com diabetes tipo 2 e em mulheres, comparativamente aos homens (Happe et al, 2016). Outras bibliografias relatam que os distúrbios do sono influenciam o controlo glicémico e um tratamento inadequado desta doença, o que pode contribuir para um controlo sub-ótimo da diabetes (Kalra & Gupta, 2018) e que esta tem sido associada a um risco aumentado de vários distúrbios vasculares (Koh et al, 2015).…”