White Infarcts of the Placenta

Intrarenal Vascular Lesions Associated with Pre-Eclampsia

“…Since fibrin deposition in the spiral arteries has been noted as early as the 10th week of normal gestation [46] and limited placental infarction has been reported in up to 25% of normal pregnancies [47] it is clear that abnormalities of placental blood flow may occur without any disturbance of fetal growth or maternal manifestations during even normal pregnancy. It is not surprising therefore that in the absence of any sensitive clinical index or investigatory procedure capable of detecting early changes in the utero-placental unit, it is difficult to establish with any degree of ac curacy whether the disturbances of placental blood flow antedate the maternal manifes tations of pre-eclampsia or whether the two phenomena occur simultaneously.…”

Ultrasonographic Diagnosis of Intervillous Thrombosis Related to Rh Isoimmunization

“…Some IVTs were first observed 6 weeks before delivery, keeping the same echoscopic aspect during the following weeks. Microscopically, these lesions had a uniform com position of red blood cells streaked with bands of fibrin, described as 'recent' IVTs by Fox (12). Other lesions were detected later in pregnancy but were already entirely hyalinized at birth.…”

“…'aging' of the thrombosis -which differs the acoustic impedance of the original thrombus. Differentiation between 'old' and 'recent' IVT (12), was echoscopically only related to the time of appearance and not to the echoscopic display of the lesion. Some IVTs were first observed 6 weeks before delivery, keeping the same echoscopic aspect during the following weeks.…”

Effects of a Thromboxane Synthetase Inhibitor (OKY-046) in an Ischemia-Reperfusion Model of Intrauterine Growth Retardation in Sprague-Dawley Rats

“…The severity of fetal growth retardation is related to the extent of placental infarction [1][2][3]. Pla cental infarction usually represents a lobular distribution and is thought to indicate the presence of extensive placental ischemia re sulting from occlusion of the spiral artery [2], These findings suggest that ischemia-reperfusion in the placental lobes exacerbate IU G R .…”