Which hemogram parameter is more cautionary in euthyroid patients with gestational diabetes mellitus

Yıldız, Saliha; Üçler, Rıfkı; Alay, Murat; Ekici, Emine Bulut

doi:10.5505/ejm.2016.66375

Cited by 5 publications

(4 citation statements)

References 16 publications

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“…However, studies of the association between MPV and GDM yielded inconsistent findings. Some studies observed that GDM patients had significantly increased MPV compared with healthy pregnant women [ 12 , 13 ], whereas other studies reported no association between MPV and GDM [ 14 , 15 ]. Furthermore, some groups found decreased MPV values in patients with GDM [ 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Zhou

Chen

Sun

et al. 2018

Journal of Diabetes Research

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Aim To evaluate the association between mean platelet volume (MPV) and gestational diabetes mellitus (GDM). Methods A systematic literature search was performed in PubMed, EMBASE, Web of Science, and The Cochrane Library up to 4 September 2017. Pooled standardized mean differences (SMD) and 95% confidence interval (CI) were calculated using a random-effect model. Results Nineteen studies comprising 1361 GDM patients and 1911 normal pregnant women were included. MPV was increased in GDM patients when compared with healthy pregnant women (SMD: 0.79; 95% CI: 0.43–1.16; P < 0.001). Subgroup analyses revealed that such trend was consistent in the third-trimester (SMD: 1.35; 95% CI: 0.72–1.98), Turkish (SMD: 0.81; 95% CI: 0.43–1.19), and Italian (SMD: 2.78; 95% CI: 2.22–3.34) patients with GDM and the patients diagnosed based on Carpenter and Coustan criteria (SMD: 1.04; 95% CI: 0.42–1.65). Significantly higher MPV also were observed within cross-sectional studies (SMD: 0.99; 95% CI: 0.49–1.49). Remarkable between-study heterogeneity and potential publication bias were observed in this meta-analysis; however, sensitivity analysis indicated that the results were not unduly influenced by any single study. Conclusions GDM patients are accompanied by increased MPV, strengthening the clinical evidence that MPV may be a predictive marker for GDM.

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Section: Introductionmentioning

confidence: 99%

Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Zhou

Chen

Sun

et al. 2018

Journal of Diabetes Research

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“…The second study, published in 2016 by Yildiz et al , reported opposite results ( 28 ). The authors performed a cross-sectional case–control study of 53 euthyroid normotensive GDM patients and 35 healthy pregnant women.…”

Section: Discussionmentioning

confidence: 97%

“…The role of RDW in predicting GDM has been evaluated recently in two studies with contrasting results ( 27 , 28 ). The first study was performed retrospectively in 68 patients with GDM and 61 healthy controls ( 27 ).…”

Section: Discussionmentioning

confidence: 99%

“…The gestational age and the definition of GDM were similar to those by Erdogan et al Several blood count indexes were found to be altered in the GDM group in this study, including RDW; the mean (SD) RDW values were 15.6% ± 1.1 and 13.0% ± 0.6 (P = 0.007) in GDM and healthy controls respectively. According to the authors, the mechanism of the increase of RDW in GDM is not clear, and may be secondary to oxidative stress and rapid erythrocyte elimination, similarly to other forms of diabetes ( 28 ). …”

Section: Discussionmentioning

confidence: 99%

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Red blood cell distribution width in pregnancy: a systematic review

et al. 2018

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Anisocytosis has been associated with the severity and prognosis of several acute and chronic diseases, as well as physiological conditions such as pregnancy. Anisocytosis is quantified by the red blood cell distribution width (RDW), expressed as the ratio, multiplied by 100, between the standard deviation (SD) of red blood cell volumes and the mean corpuscular volume, or as the SD of erythrocyte volumes (RDW-SD). The aim of the present review was to report the state of the art on the physiological values and the putative diagnostic and prognostic roles of RDW in complicated pregnancy. Literature research for articles published in the last ten years was conducted in Pubmed, Web of Science, ClinicalTrials.gov, and Scopus databases. Abstracts were independently screened by two investigators. If relevant, full articles were retrieved. References, in these articles, citing relevant reviews or original studies were also accessed to identify additional eligible studies. Any disagreement between the reviewers was resolved by a third investigator. A total of 28 studies were included in the review. These studies reported changes in RDW values during physiological pregnancy, and associations between the RDW and several pregnancy complications including anaemia, preeclampsia, gestational diabetes, and recurrent miscarriage. This review provides background information for establishing physiological and pathological RDW values in pregnancy for diagnostic and prognostic use in clinical practice.

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Association Between Red Blood Cell Distribution Width in Late Pregnancy and the Incidence of Adverse Perinatal Outcomes: A Retrospective Cohort Study

Zhang,

Han,

Long

et al. 2024

Archives of Medical Research

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Which hemogram parameter is more cautionary in euthyroid patients with gestational diabetes mellitus

Cited by 5 publications

References 16 publications

Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Red blood cell distribution width in pregnancy: a systematic review

Association Between Red Blood Cell Distribution Width in Late Pregnancy and the Incidence of Adverse Perinatal Outcomes: A Retrospective Cohort Study

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