Inequality in length of life is the most fundamental of all inequalities; every other type of inequality is conditional upon being alive. As has long been recognized in studies of economic inequality, we can compare populations based on per capita gross national income, but there is a pressing need to further examine how income varies within populations via Gini coefficients and percentile-based metrics. Mortality inequalities should be approached in the same way. Human population health is generally monitored by average mortality levels, typically in terms of life expectancies, which belie substantial variation in length of life. Variation in ages at death, captured by a metric of lifespan variation, should be used to supplement measures of average longevity when comparing or monitoring societies and population subgroups (1). Although lifespan variation has historically been strongly inversely correlated with life expectancy (2, 3), we are beginning to see this relationship reversed, resulting in positive correlation in some countries or subnational populations. Often these changes reflect midlife mortality crises with roots in stratified education and wealth. We discuss these measures and trends and how they can have profound implications for how individuals might plan and live their lives, and for how societies might organize and manage health care, insurance, pensions, and other social policies and programs. Life expectancy at birth (or simply life expectancy, as we refer to it in the rest of the text) is the most common metric of survival. It is the hypothetical average age at death given age-specific death rates in a given year. Lifespan variation, the variability in ages at death around that average, can be measured by using an index of variation or inequality-for instance, the standard deviation, Gini coefficient, or interquartile range. To illustrate, consider age-at-death distributions of non-Hispanic black and non-Hispanic white men in the United States based on 2012-2016 death rates. The life expectancy from this distribution is 72 years for blacks and 77 years for whites [see supplementary materials (SM)]. But the timing of death was variable, skewed below the average in both groups, meaning that deaths were more spread out below the life expectancy than above it. Among blacks, the spread in survival was noticeably wider. Men in the 25th to 75th percentile (the interquartile range) died between 63 and 85 years in the black distribution, whereas those in the white distribution died between 69 and 88 years. Although life expectancy for blacks was only 6% lower than for whites, the age window over which these deaths occurred was 17% larger for blacks. Some early efforts by the Organization for Economic Cooperation and Development (OECD) to monitor within-group variability included a one-off report that measured lifespan variation conditional upon survival to age 10 (4). However, although we currently monitor life expectancy at birth in all countries of the world, which captures between-country differenc...