Where are We on Organ Donation?

Abstract

Adıyaman Üniversitesi Eğitim ve Araştırma Hastanesi, yoğun bakım ünitesinde beyin ölümü tanısı konulan olguların demografik ve klinik özellikleri retrospektif olarak incelenerek, organ bağışı kabul oranları sunuldu. Gereç ve Yöntem: Hastanemiz yoğun bakım ünitesinde 2008-2014 yılları arasında beyin ölümü tanısı konmuş hastalar retrospektif olarak incelendi. Tüm hastalar; yaş, cinsiyet, beyin ölümü nedeni, kan grubu, organ bağışı kabul ve red nedenleri, kardiyak arrest geçirme ve vazopressin kullanma durumu, laboratuvar testleri, apne testi öncesi ve sonrası kan gazı değerleri, yoğun bakımda izlem süresi, apne testi, yıl ve mevsimsel dağılım açısından değerlendirildi. Donör adayı olan olgular verilen organ ve alıcı olan hastalar demografik özelliklerine göre ayrıca değerlendirildi. Bulgular: Otuz dört (%59,6) erkek, 23 (%40,4) kadın toplam 57 hastaya beyin ölümü tanısı konuldu. En sık nedenler travmatik subaraknoid kanama (SAK) ve intraserebral hematom idi. Olguların çoğu A Rh (+) kan grubunda (n=18, %31,5) idi. Rh (+) hastalarda Rh (-) hastalara oranla 4,7 kat fazla beyin ölümü tespit edildi. Kardiyak arrest görülme oranı %12,3 (n=7) olup en sık SUMMARY Objective: It was aimed to present the acceptance rate of organ donation of cases that were diagnosed with brain death and evaluated in terms of their demographic and clinical properties retrospectively in Adıyaman University Training and Research Hospital. Material and Method: In the intensive care unit of our hospital, cases that were diagnosed with brain death between the dates of January 2008 and December 2014 were retrospectively analyzed. Cases were evaluated in terms of age, sex, cause of brain death, blood groups, donation status, reasons for acceptance or rejection of donation, cardiac arrest, vasopressin treatment, laboratory test results, arterial blood gas values before and after the apnea test, intensive care unit follow-up durations, apnea test, seasonal and annual distribution. Also, potential donors and recipients were analyzed in accordance with their demographic characteristics. Results: The diagnosis of brain death was made in totally 57 cases; of those, 34 (59.6%) were men and 23 (40.4%) were women. The most common causes for brain death were traumatic subarachnoid hemorrhage (SAH) and intracerebral hematoma. Most of the cases had A Rh+ blood type (n=18, 31.5%) and the rate of brain death was 4.7 times higher in Rh (+) patients in comparison to Rh (-) patients. The rate of incidence of cardiac arrest was 12.3% (n=7), and it was more common in traumatic SAH patients. The rate of receiving vasopressor therapy was 21.1% (n=12), and the mean duration of therapy was 1.3±0.8 days. It was more commonly used in traumatic SAH patients (n=10). The follow-up period was 2.7±3.2 (minimum: 1, maximum: 17) days. Five patients were considered to be organ donors. The most common reason for acceptance of donation was the effect of organ transplantation coordinator during family interviews (n=3, 60%). In total, 4 livers, 5 kidneys and 1 heart transplantation oper...

Brain Death and Organ Donation Rates in a City Hospital: A Retrospective Study

“…Intracerebral hemorrhage was the most common cause of brain death in our study, similar to the studies by Escudero et al [13] and Pandey et al [3]. However, many studies reported different primary causes of brain death [14-15,19]. The difference in the most common cause of brain death in various studies may be a result of using different classifications for the cause of brain death.…”

Retrospective analysis of the patients with brain death diagnosis in the last 5 years in our hospital

“…Gender varies between countries in patients diagnosed with brain death. In our study, 52.3% of patients diagnosed with brain death were female gender; studies conducted in our country reported that the majority of those diagnosed with brain death are male sex 7,8,9,10 . Aghighi et al 11 reported from Iran that the rate of brain death in males was 2.1 times that of females and Han et al 12 in a study conducted in South Korea; women were more diagnosed with brain death (65%).…”

“…Karasu et al 7 reports that; Of the 79 patients diagnosed with brain death during a 7-year period in Bursa Yüksek İhtisas Training and Research Hospital, 27 (34.2%) of the families gave consent to organ donation, Kıraklı et al 8 in a study conducted for past 2 years in Izmir Tepecik Education and Research Hospital in 48 out of 1759 patients were found to be diagnosed with brain death, and 33 patients (69%) found that their relatives accept organ donation. Uludağ et al 9 reported that 59 patients were diagnosed with brain death between 2008 and 2014 in Adıyaman University Training and Research Hospital, and five patients (8.7%) were donors. Han et al 12 examined 107 cases with brain death and found that the organ donation rate was 58% (n: 62).…”

Retrospective Investigation of Brain Death and Organ Donation Cases in a Training and Research Hospital

“…Uludağ ve ark. [15] tarafından Adıyaman'daki bir eğitim ve araştırma hastanesinde gerçekleştirilen çalışmada olguların %59.6'sı erkek, %31.5'i A kan grubu bulunmuştur. Hastaneye yatış tanıları açısından incelendiklerinde ise subaraknoid kanama (%42) ve intraserebral hematom (%14) ilk sıralardadır.…”