When to Start Antifungal Therapy in the Non-Neutropenic Critically III?

Tuboovarian abscess caused by Candida glabrata in a febrile neutropenic patient

“…2 Deep-seated Candida infections are strongly associated with mortality and morbidity of patients, and need early diagnosis and treatment. [3][4][5] Advances in medical technology and anticancer chemotherapies have enabled long-term survival for patients, 6,7 yet increased numbers of deep-seated Candida infections in immunocompromised hosts might become a direct cause of death. 7 …”