When abdominal pain knocks the door: an unusual presentation of chronic lymphocytic leukemia

Abstract

A 67-year-old man presented non-specific abdominal pain. Polypoid mass at appendiceal orifice in the cecum was found on endoscopic investigation without appendicitis sign. Histopathology elucidated underlying mucosal infiltration that was chronic lymphocytic leukemia. This is an isolated and unusual gastrointestinal involvement of hematologic disorder in an older patient.

Routine GI Endoscopy

“…Discussion: Several previous case reports and series have noted gastrointestinal tract involvement with CLL, 6 including a non-ulcerated cecal polypoid lesion found to be infiltrated by CLL, rectal inflammation associated with irregular and occasionally ulcerative surface mucosa, and histological findings consistent with CLL infiltrates, often with normal colonic mucosae. 1,[5][6][7] CLL has been shown to occur concurrently with a rectal cancer but without apparent causal linkage. Background and Aim: For an outpatient endoscopy assessment clinic for patients referred by general practitioners or other specialists for consideration of endoscopy, the coronavirus disease 2019 (COVID-19) pandemic necessitated a move from face-to-face to a virtual format, including telehealth and telephone models.…”

A Brief Review of the Progress of Research on Late Pain Care in Patients with Leukemia

“…Medical staff should try not to choose patients' rest time in the examination of patients, to keep the operation of the soft, reduce the stimulation; The related stents were used to improve the comfort level of patients in dressing change, catheterization, enema and other nursing operations. According to the changes in external air temperature, the appropriate temperature and humidity in the ward would be ensured, so as to eliminate the stimulation caused by overheating, supercooling, and excessively dry room to the patients and increase the pain perception [16] .…”

Lymphoepithelioma-Like Gastric Carcinoma and Gastric Involvement of Chronic Lymphocytic Leukemia: Two Rare Identities Coexisting in One Patient

“…Chronic lymphocytic leukemia (CLL) accounts for approximately 25% of adult leukemias in the western world. The reports of CLL cases involving infiltration of the gastrointestinal tract are relatively rare in the literature, and the estimated incidence ranges from 5.7% to 25% in patients with CLL [ 3 - 5 ].…”