What Would Digital Early Intervention for Bipolar Disorder Look Like? Theoretical and Translational Considerations for Future Therapies

Murray, Greg

doi:10.3389/fpsyt.2019.00599

Cited by 12 publications

(8 citation statements)

References 82 publications

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“…To maximise engagement, it is useful to encourage the young person to set positive, personally relevant goals for treatment, such as improved relationships with peers. More broadly, it is important for clinicians to be sensitive to the developmental context of adolescent BD, ensuring treatment is meaningful to the young person (Murray, 2019b). An example of a structured intervention that contains all these elements is Family-Focused Treatment for Adolescents (Miklowitz et al, 2004).…”

Section: Children and Adolescentsmentioning

confidence: 99%

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Malhi

Bell

Bassett³

et al. 2020

Aust N Z J Psychiatry

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327

365

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Objectives: To provide advice and guidance regarding the management of mood disorders, derived from scientific evidence and supplemented by expert clinical consensus to formulate s that maximise clinical utility. Methods: Articles and information sourced from search engines including PubMed, EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (e.g. books, book chapters and government reports) and from published depression and bipolar disorder guidelines. Relevant information was appraised and discussed in detail by members of the mood disorders committee, with a view to formulating and developing consensus-based recommendations and clinical guidance. The guidelines were subjected to rigorous consultation and external review involving: expert and clinical advisors, key stakeholders, professional bodies and specialist groups with interest in mood disorders. Results: The Royal Australian and New Zealand College of Psychiatrists mood disorders clinical practice guidelines 2020 (MDcpg2020) provide up-to-date guidance regarding the management of mood disorders that is informed by evidence and clinical experience. The guideline is intended for clinical use by psychiatrists, psychologists, primary care physicians and others with an interest in mental health care. Conclusion: The MDcpg2020 builds on the previous 2015 guidelines and maintains its joint focus on both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Mood disorders committee: Gin S Malhi (Chair), Erica Bell, Darryl Bassett, Philip Boyce, Richard Bryant, Philip Hazell, Malcolm Hopwood, Bill Lyndon, Roger Mulder, Richard Porter, Ajeet B Singh and Greg Murray.

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Section: Children and Adolescentsmentioning

confidence: 99%

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Malhi

Bell

Bassett³

et al. 2020

Aust N Z J Psychiatry

Self Cite

327

365

View full text Add to dashboard Cite

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“…As a result, MHAs may assist in increasing access to support for young adults who have a family history of mental illness. However, there is no literature which investigates how young at‐risk individuals use MHAs, despite the increasing need to introduce digitally based treatments and interventions to this population (Murray, 2019).…”

Section: Introductionmentioning

confidence: 99%

Mental health mobile application usage in young adults with a family history of mental illness

Schlage

Perich

2020

Australian Psychologist

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Objective: Young adults with a family history of mental illness are at increased risk of developing mental disorders. The current study aimed to assess how young at-risk individuals use mental health applications (MHAs) in comparison with those not at-risk, and whether these groups differed in the types of MHAs used, how helpful they found MHAs, and their reasons for and against using MHAs. Method: An online survey was conducted where young adults aged 18-30 years (N = 525; 389 female) were asked about their immediate family history of any diagnosis of any mental illness and their use of MHAs. The responses were analysed using chi-square tests of independence. Results: Young adults with a family history of mental illness (N = 271) were more likely to report using MHAs and more likely to use MHAs for mental wellbeing than those who did not have a family history of mental illness. They were also more likely not to use MHAs if they were not useful or did not want to use them. Individuals who identified as "other" genders were also more likely to use MHAs while males were less likely to use MHAs. Conclusions: MHAs may be a viable avenue to engage at-risk individuals in targeted treatment and suggests the need to develop apps tailored to this population. It is recommended that future research explores the efficacy of MHAs in reducing psychiatric symptomatology in the at-risk population, and how apps may be used by clinicians most effectively as part of treatment. K E Y W O R D S at-risk, family history, mental health, mobile app, mobile technology 1 | INTRODUCTION Young adults with a family history of mental illness may be particularly vulnerable to mental illness, being more likely to develop a mental health condition due to increased genetic vulnerability and environmental factors, and being less likely to receive treatment or support (Bandelow et al.

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“…Potential implications of this finding include adding granularity to existing staging proposals. For example, adding data about individuals scores on well‐validated measures assessing current phenomenology to information about their diagnosis and course of illness (“stage”) may prove to be informative for selecting appropriate treatments (eg, adjunctive psychosocial treatments with differing intensities or foci), in line with a stepped care ideology 44,45 . To achieve this aspiration, confirmation of phenomenology‐based subgroups in other samples is required.…”

Section: Discussionmentioning

confidence: 99%

Conceptualizing the later stage of bipolar disorder: Descriptive analyses from the ORBIT trial

2020

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Objectives This study aimed to investigate the features of later stage bipolar disorder (BD) and specifically, factors underlying later stage BD and potential subgroups within this stage, to understand more about the later stage group and contribute to the measurement of stage. Methods An exploratory factor analysis was conducted using variables relating to current phenomenological aspects of illness, followed by cluster analyses based on the identified factors. Finally, the resultant clusters were compared based on course of illness variables. Results Fourteen extracted factors explained 57 percent of the variance. Latent structures aligned with current depressive symptoms, energy and interest, independence, occupational functioning, symptoms of anxiety, pain, elevated symptoms, interpersonal functioning, anger, perceptions of social connections, and perceptions of current medication effectiveness, cognitive issues, sleep issues, and sense of isolation. Two clusters were identified which differed significantly on each of these factors, and on a range of course of illness features including lifetime number of episodes, duration of illness and number of depressive hospitalizations. Conclusions Latent phenomenological features relevant to individuals in the later stage of BD were identified. Two clusters of individuals in later stage BD differ based on these features as well as course of illness, suggesting that there are distinct subgroups of individuals in the later stage of BD, distinguishable based on current phenomenology and illness history. However, findings are exploratory and therefore require confirmation before they can be applied clinically.

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What Would Digital Early Intervention for Bipolar Disorder Look Like? Theoretical and Translational Considerations for Future Therapies

Cited by 12 publications

References 82 publications

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Mental health mobile application usage in young adults with a family history of mental illness

Conceptualizing the later stage of bipolar disorder: Descriptive analyses from the ORBIT trial

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