What is the most important component of blood pressure: systolic, diastolic or pulse pressure?

Strandberg, Timo; Pitkälä, Kaisu

doi:10.1097/00041552-200305000-00011

Cited by 154 publications

(118 citation statements)

References 43 publications

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“…We considered a cutoff of 50 mmHg based on two studies that found an increased cardiovascular risk with this level of PP 16,33 . Although the positive association between PP and cardiovascular risk has been largely demonstrated 34 , there are discordant results in literature, but the evidence points out to the existence of an increased risk in patients with elevated SAH and PP 35 . As observed by Lurbe et al 36 , around 50% of the adolescents who presented elevated PP were normotensive, thus representing a lower risk 35 .…”

Section: Discussionmentioning

confidence: 97%

“…Although the positive association between PP and cardiovascular risk has been largely demonstrated 34 , there are discordant results in literature, but the evidence points out to the existence of an increased risk in patients with elevated SAH and PP 35 . As observed by Lurbe et al 36 , around 50% of the adolescents who presented elevated PP were normotensive, thus representing a lower risk 35 . The increase of PP in the studied population occurred from the increase of SAP, which is more common among adolescents 25 .…”

Section: Discussionmentioning

confidence: 97%

“…In elderly individuals, it has been associated with the stiffening of arteries and atherosclerosis of the great arteries, demonstrated as the intima-media thickening (IMT) 35,37 . The arterial stiffening as well as the IMT have shown to be associated with increased morbidity and mortality 38,39 .…”

Section: Discussionmentioning

confidence: 99%

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Pré-hipertensão arterial e pressão de pulso aumentada em adolescentes: prevalência e fatores associados

Rosa¹,

Fonseca²,

Oigman³

et al. 2006

Arq. Bras. Cardiol.

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OBJECTIVETo estimate the prevalence of prehypertension and elevated pulse pressure in adolescents and assess the association between those two conditions and sex, age, sexual development, obesity and physical activity. METHODSAnthropometrical data and blood pressure were measured in and a questionnaire was applied to 456 adolescents (aged 12 to 17 years) recruited from public and private schools, in the Fonseca district, in the city of Niterói, state of Rio de Janeiro, Brazil, from 2003 to 2004. RESULTSThirty nine (8.6%) presented prehypertension (PH) and 13.4%, elevated pulse pressure (PP). At bivariate analysis, PH was signifi cantly associated with sex, age and obesity, with more prevalent in boys aged between 15 and 17 years, and in the obese. Elevated PP was associated with gender only, as it was more prevalent in boys. Sexual maturation did not show an association with PH or elevated PP. Similar correlations were found at logistic regression. PH prevalence odds ratio was 7.7 for sex, 4.3 for age and 4.6 for obesity. Elevated PP prevalence odds ratio was 10.8 for sex. The correlation between PP and physical activity was positive and signifi cant. The elevation of PP was attributable to systolic blood pressure. CONCLUSIONPH and the elevated PP were shown to be present in adolescents from a population with a low prevalence of hypertension, mostly in boys. Further prospective studies are necessary to assess the persistence and the impact of those conditions.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 97%

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Pré-hipertensão arterial e pressão de pulso aumentada em adolescentes: prevalência e fatores associados

Rosa¹,

Fonseca²,

Oigman³

et al. 2006

Arq. Bras. Cardiol.

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“…37 SBP might be an informative indicator considering the cardiovascular risk as isolated SBP has been associated with increased mortality risk in several studies, especially in the middle-aged population. 38 Hypoadiponectinaemia is related to the development of insulin resistance. 7 Therefore, the effect of high adiponectin on SBP may be mediated through lowering of insulin resistance.…”

Section: Discussionmentioning

confidence: 99%

Plasma adiponectin concentration is associated with ambulatory daytime systolic blood pressure but not with the dipping status

2009

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The objective of this study was to analyse the relationship between the ambulatory blood pressure (ABP) measurement and plasma adiponectin levels in a population-based cohort. Non-hypertensive, non-diabetics from the Oulu Project Elucidating Risk of Atherosclerosis cohort aged 40-60 years with ABP measurement available in 226 men and 236 women were analysed. ABP was recorded using the fully automatic SpaceLabs 90207 oscillometric unit. Plasma adiponectin concentrations were assayed using the enzyme-linked immunosorbent assay method. Without adjustment the highest plasma adiponectin tertile was associated with the lowest ABP and office BP measurements (P from 0.025 to Po0.001, respectively). Only the association of plasma adiponectin concentration with systolic ABP was independent of other conventional risk factors (age, body mass index (BMI), waist, gender, insulin sensitivity index, smoking and alcohol consumption) for hypertension (P ¼ 0.017). No association was observed between systolic dipping pattern and adiponectin level. The plasma high adiponectin concentration is independently associated with low daytime systolic ABP value. The mechanisms may include effects on endothelial function and the sympathetic nervous system.

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“…It has been suggested as the primary target of antihypertensive treatment [18]. SBP was assessed at age 24 years by trained technicians using standardized methods [19].…”

Section: Study Variablesmentioning

confidence: 99%

Relationships Between Current and Past Binge Drinking and Systolic Blood Pressure in Young Adults

Wellman

Vaughn

Sylvestre

et al. 2016

Journal of Adolescent Health

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A B S T R A C TPurpose: Heavy episodic (i.e., "binge") drinking (i.e., !five drinks/occasion) is highly prevalent among young adults; those who binge do so four times per month on average, consuming nine drinks on average on each occasion. Although it is well established that chronic heavy drinking (!two alcoholic beverages per day) increases the risk of hypertension, the relationship between binge drinking and blood pressure is not well described. Our aim was to describe the relationship between frequency of binge drinking, both current (at age 24 years) and past (at age 20 years), and systolic blood pressure (SBP) at age 24 years. Methods: Participants (n ¼ 756) from the longitudinal Nicotine Dependence in Teens study reported alcohol consumption at ages 20 and 24 years and had SBP measured at age 24 years. We examined the association between binge drinking and SBP using multiple linear regression, controlling for sex, race/ ethnicity, education, monthly drinking in high school, cigarette smoking, and body mass index. Results: Compared to nonbinge drinkers, SBP at age 24 years was 2.61 [.41, 4.82] mm Hg higher among current monthly bingers and 4.03 [1.35, 6.70] mm Hg higher among current weekly bingers. SBP at age 24 years was 2.90 [.54, 5.25] mm Hg higher among monthly bingers at age 20 years and 3.64 [.93, 6.35] mm Hg higher among weekly bingers at age 20 years, compared to nonbinge drinkers. Conclusions: Frequent binge drinking at ages 20 and 24 years is associated with higher SBP at age 24 years and may be implicated in the development of hypertension.

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What is the most important component of blood pressure: systolic, diastolic or pulse pressure?

Cited by 154 publications

References 43 publications

Pré-hipertensão arterial e pressão de pulso aumentada em adolescentes: prevalência e fatores associados

Pré-hipertensão arterial e pressão de pulso aumentada em adolescentes: prevalência e fatores associados

Plasma adiponectin concentration is associated with ambulatory daytime systolic blood pressure but not with the dipping status

Relationships Between Current and Past Binge Drinking and Systolic Blood Pressure in Young Adults

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