What is the evidence for gender differences in ferritin and haemoglobin?

Rushton, D. H.; Barth, Julian H.

doi:10.1016/j.critrevonc.2009.03.010

Cited by 102 publications

(94 citation statements)

References 81 publications

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“…1, 2006, to Aug. 31,2006, from 44 general practices in France. In total, 243 patients were screened for eligibility.…”

Section: Resultsmentioning

confidence: 99%

“…30 The appropriateness of the official definition of the lower limit for normal hemoglobin concentrations in women has been debated. 31 The biological definition of iron-deficiency anemia is based on the reduction of erythropoiesis due to a lack of available iron. Hemoglobin cutoff values serve as a surrogate and do not truly reflect all individuals' erythropoietic function correctly.…”

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confidence: 99%

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Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Vaucher

Druais

Waldvogel

et al. 2012

CMAJ

126

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“…1, 2006, to Aug. 31,2006, from 44 general practices in France. In total, 243 patients were screened for eligibility.…”

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Vaucher

Druais

Waldvogel

et al. 2012

CMAJ

126

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“…Therefore, iron recycling accounts for most of the iron homeostasis in human. The situation is different in menstruating women [62,63] where there are controversial discussions about iron stores, ferritin, and Hb levels [64,65]. It appears that lower Hb and ferritin values in menstruating women have been accepted as normal rather than possibly representing widespread iron deficiency.…”

Section: Iron In the Bodymentioning

confidence: 99%

Physiology of Iron Metabolism

Waldvogel-Abramowski

Waeber²,

Gassner³

et al. 2014

Transfus Med Hemother

204

146

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A revolution occurred during the last decade in the comprehension of the physiology as well as in the physiopathology of iron metabolism. The purpose of this review is to summarize the recent knowledge that has accumulated, allowing a better comprehension of the mechanisms implicated in iron homeostasis. Iron metabolism is very fine tuned. The free molecule is very toxic; therefore, complex regulatory mechanisms have been developed in mammalian to insure adequate intestinal absorption, transportation, utilization, and elimination. ‘Ironomics' certainly will be the future of the understanding of genes as well as of the protein-protein interactions involved in iron metabolism.

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“…In many cultures where iron kitchenware is used, women present elevated levels of haemoglobin (19.4 g/dL in Ethiopian women) [32], such as in our grandmothers' time because they cooked with iron kitchenware and they had iron diet. Later it was proved the decreased haemoglobin values are not "normal" for the women.…”

Section: Discussionmentioning

confidence: 99%

Ferritin: Could be a Health Indicator

M¹,

L²

2018

J Fam Med Dis Prev

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• AbstractHealth indicators show a health-related characteristic that allows the study, evaluation and conclusion of a health process. Therefore, it allows us to influence public health policies to obtain an improvement in the health status of the population.Iron deficiency is one of the most prevalent forms of malnutrition, without quality of life and can present in anaemia, with reduce of hemoglobin (it causes 50% of anaemia around the world) and in ferropenia, iron deficiency, without anaemia. The iron deficiency has a very heavy rates of mortality associated of it.The iron element is a d-block transition element with an oxidation changeable ranging between -2 and 6+ which makes iron to be in different biological ways: ferrous (Fe 2+ ), ferric (Fe 3+ ), or ferryl (Fe. This capacity allows iron to bind to manifold ligands/proteins of the human organism, which are essential for all living cells; to participate in many metabolic and energetic pathways, like a production of energy in mitochondria, binding and transport of oxygen, regulation of cell growth and differentiation, synthesis and packaging of neurotransmitters and degradation of catecholamines [2], synthesis of the deoxyribonucleic acid or DNA [3] and others.As free iron is toxic to cells, it is stored complexed to protein as ferritin. Thus, the serum ferritin level correlates with a total body iron, could discard ferropenia (iron deficiency without anaemia) and establish he quality of life.Women, especially in their fertile stage, tend to have lower values because of menstrual losses, even during normal menses. In this small text we will try to reflect on how ferritin can be a parameter of evaluation of quality of life and normality of body functions.

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What is the evidence for gender differences in ferritin and haemoglobin?

Cited by 102 publications

References 81 publications

Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Physiology of Iron Metabolism

Ferritin: Could be a Health Indicator

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