Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Vaucher, Paul; Druais, Pierre-Louis; Waldvogel, Sophie; Favrat, Bernard

doi:10.1503/cmaj.110950

Cited by 126 publications

(114 citation statements)

References 32 publications

(35 reference statements)

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“…19 Verdon et al also documented that there was significant improvement in fatigue following iron supplementation in non-anaemic women with unexplained fatigue. 20 Hence, iron supplementation may be considered in family OPDs/MI Rooms of Military hospitals for women with unexplained fatigue who have normal haemoglobin levels but have underlying low ferritin levels.…”

Section: Discussionmentioning

confidence: 95%

Low prevalence of anaemia among the wives of serving personnel in a military station: A community-based study

Dudeja

Tewari

Singh

et al. 2016

Medical Journal Armed Forces India

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m e d i c a l j o u r n a l a r m e d f o r c e s i n d i a 7 2 ( 2 0 1 6 ) 3 5 6 -3 6 1 a r t i c l e i n f o Background: Various studies in India have reported the prevalence of anaemia to be more than 50% among women of the reproductive age group. A community-based study was done to find out the prevalence of anaemia in non-pregnant, non-lactating wives of serving soldiers in a military station.Methods: It was a cross-sectional study. The sample size was 600. Venous blood was collected for haemoglobin and ferritin levels. Analysis was done by SPSS 20. Results:The mean age at marriage was 19.8 years (SD + 2.76). The average age at first childbirth was 20.88 years. Major symptoms reported were weakness (24.34%), giddiness (23.47%), fatigue (20.17%) and heavy bleeding (3.13%). Prevalence of anaemia in our study was 13.9%, which is much below the national prevalence. Prevalence of iron-deficient status was reported in 153 (26%) individuals. Out of these, 81 subjects were non-anaemic (Hb > 12d/dL) but were iron deficient (ferritin <15 mg/L). Sixty out of these 81 subjects reported presence of fatigue and 36 had weakness. Statistically significant associated observations of anaemia were low Body Mass Index, irregular menstrual pattern, shortened menstrual cycle and increased duration of bleeding ( p < 0.05). Low ferritin levels were significantly associated with low BMI, not using Oral Contraceptive Pills and bleeding for more than 3 days during menstrual cycle ( p < 0.05). Conclusion:The scenario of low prevalence of anaemia in women under the cover of the Armed Forces Medical Services represents an 'island of excellence'. #

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Section: Discussionmentioning

confidence: 95%

Low prevalence of anaemia among the wives of serving personnel in a military station: A community-based study

Dudeja

Tewari

Singh

et al. 2016

Medical Journal Armed Forces India

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“…However, no association was found in premenopausal women (Hunt and Penland, 1999) and iron levels were not associated with the onset of post-partum depression (Armony-Sivan et al, 2012). The antidepressant benefits of iron supplementation on adults are scarce and are again, inconsistent with both positive (Verdon et al, 2003) and negative (Vaucher et al, 2012) findings.…”

Section: Iron and Depressionmentioning

confidence: 98%

A review of nutrient treatments for paediatric depression

Lopresti

2015

Journal of Affective Disorders

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Paediatric depression is estimated to affect 15 to 20% of youths prior to adulthood and is associated with significant social, educational and physical impairment. Current treatments comprise moderately efficacious psychological therapies and pharmaceutical antidepressants. However, nutritional therapies are also available and are regularly sought by people with depressive illnesses and parents of depressed youths. In this narrative review, studies examining the antidepressant effects of individual nutritional supplements in child and adolescent populations are appraised.Epidemiological studies examining the relationship between nutritional status and paediatric depression, or depressive symptoms are also reviewed. Nutrients covered in this article include: omega-3 polyunsaturated fatty acids, s-adenosylmethionine, vitamin C, vitamin D, zinc, iron and Bvitamins. Although several of these nutrients present as promising treatments for paediatric depression, there is a lack of high-quality studies examining the antidepressant effects of all the aforementioned ingredients. Before nutritional treatments are accepted as validated treatments for paediatric depression, further high-quality studies are required.

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“…The minerals presented in the formula were chelated into an amino acid (glycine). The micronutrient supplementation of 2 RDAs (26) was suggested to be given daily for RYGB surgery in two doses (11,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35). Adequate Intake (AI) (26) was used when the RDA was not established for the micronutrient (except for calcium).…”

Section: Micronutrient Supplementationmentioning

confidence: 99%

Micronutrient supplementation in gastric bypass surgery: prospective study on inﬂammation and iron metabolism in premenopausal women

et al. 2017

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Marin FA, Verlengia R, Crisp AH, Sousa Novais PF, Rasera-Junior I, de Oliveira MR. Micronutrient supplementation in gastric bypass surgery: prospective study on infl ammation and iron metabolism in premenopausal women. Nutr Hosp 2017;34:369-375 DOI: http://dx.doi.org/10.20960/nh.1162 Paulo -FAPESP (Process no. 2012/18719-9) and Conselho Nacional de Desenvolvimento Científi co e Tecnológico -CNPq (Processs no. 142828/2011-4 Financial support: Fundação de Amparo à Pesquisa do Estado de São AbstractBackground: Low-grade chronic infl ammation in morbid obesity is associated with impaired iron metabolism. Bariatric surgery is effective in weight loss; however, it can induce specifi c nutritional defi ciencies, such as iron, especially in premenopausal women. Alternatively, after surgery, there is an improvement in systemic infl ammation, raising questions concerning the dosages of micronutrient supplementation. Objectives: This study aimed to assess the effect of two micronutrient supplementation schemes before and 6 months after a Roux-en-Y gastric bypass (RYGB) surgery on infl ammation and iron metabolism in premenopausal women.

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Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial

Cited by 126 publications

References 32 publications

Low prevalence of anaemia among the wives of serving personnel in a military station: A community-based study

Low prevalence of anaemia among the wives of serving personnel in a military station: A community-based study

A review of nutrient treatments for paediatric depression

Micronutrient supplementation in gastric bypass surgery: prospective study on inﬂammation and iron metabolism in premenopausal women

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