What Is ???Normal??? Blood Pressure in the Aged?

Babu, T Naresh; Nazir, Fadil; Rao, DC; Luisada, Aldo A.

doi:10.1097/00132586-197710000-00037

Cited by 3 publications

(4 citation statements)

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“…Surveys in developed countries indicate that systolic blood pressure rises with age (1–3). Since essential hypertension (the predominant type) can produce cardiovascular disease and thus increase the mortality rate (4, 5), the development of anadequate treatment program based on etiology would be of great value.…”

supporting

confidence: 93%

Changes in Hormonal Activities Relative to the Severity of Essential Hypertension

Ito

Kubota

Yamada

et al. 1979

J American Geriatrics Society

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Endocrine activity in patients with essential hypertension was studied by measuring the urinary excretion of catecholamines, prostaglandin E (PGE) and cyclic adenosine monophosphate (cAMP). Simultaneously, plasma renin activity, concentrations of serum sodium, potassium, blood urea nitrogen (BUN) and creatinine were determined. Systolic blood pressure and BUN increased progressively with age until the sixth decade. Urinary excretion of norepinephrine was correlated with the systolic blood pressure. In contrast, plasma renin activity and urinary excretion of PGE decreased progressively with the increase in systolic blood pressure. Although the cause of essential hypertension is not known, it is suggested that hypertension accelerates the aging process in the kidney and thus decreases renal PGE synthesis. This decrease of PGE in turn causes a reduction of plasma renin activity, possibly either by accelerating the retention of sodium and water or by failing to stimulate renin synthesis. A decrease of PGE may also potentiate the vasopressor action of norepinephrine.

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supporting

confidence: 93%

Changes in Hormonal Activities Relative to the Severity of Essential Hypertension

Ito

Kubota

Yamada

et al. 1979

J American Geriatrics Society

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“…However, 11% were obese by the doctor's definition and this is higher than that reported in the literature for this age group (6%-8%), (2,19). However, 11% were obese by the doctor's definition and this is higher than that reported in the literature for this age group (6%-8%), (2,19).…”

Section: Discussioncontrasting

confidence: 56%

“…Both the clinicians and the epidemiologists need to review the appropriateness of present accepted definitions of 16. hypertension in the elderly and their subsequent clinical implications, since this issue is still debatable (2,6,9,20). While the etiology of essential hypertension is still not completely elucidated, the relationships with age, sex and ethnic origin throw 15. some light on the question.…”

Section: Discussionmentioning

confidence: 99%

Blood pressure and hypertension in an elderly population

et al. 1990

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In order to study the epidemiology of hypertension in the elderly and its relationship to other disease situations, a study was performed on 815 institutionalized elderly people indicating a statistically significant decrease of both systolic and diastolic blood pressure with age. There is a difference between the population originating in Europe and America and those from Asia and Africa; in the latter group the blood pressure values were significantly higher, specially in females. The prevalence of hypertension as a disease does not differ between younger and older age groups. The lower prevalence in the population studied (28.1%) when compared to data in the literature which indicates prevalence of about 40%, might be due to the fact that the institution population live under sheltered conditions and close medical follow up. In conclusion hypertension in the elderly serves as a major risk factor for several disease situations thus leading to a better survival for those with lower values of blood pressure.

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“…Babu et al [1977] recently demonslrated that blood pressure values in 70-to 90-year-old unselected subjects re mained within the limits that are judged nor mal for younger people. Therefore, we arbi trarily considered as hypertensive elderly pa tients those having blood pressures regularly found above 160/85 mm Hg.…”

Section: Discussionmentioning

confidence: 99%

Relationships between Blood Pressure and Plasma Renin, Aldosterone and Dopamine-β-Hydroxylase in the Elderly

Annat¹,

Vincent²,

Tourniaire³

et al. 1981

Gerontology

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Plasma renin activity (PRA), aldosterone (PA) and dopamine-β-hydroxylase activity (DBH) were measured in 49 subjects over 70 years of age, selected for normal or high blood pressure level. By comparison with younger controls, elderly subjects exhibited lower supine or upright PRA, but similar PA and DBH. No relationship could be found between individual blood pressure, and PRA, PA or DBH. The data favor the view that the renin-angiotensin-aldosterone system does not play an important causative role in elderly hypertension. They also point to the necessity of age-matched controls when this system is being studied in elderly patients.

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What Is ???Normal??? Blood Pressure in the Aged?

Cited by 3 publications

References 0 publications

Changes in Hormonal Activities Relative to the Severity of Essential Hypertension

Changes in Hormonal Activities Relative to the Severity of Essential Hypertension

Blood pressure and hypertension in an elderly population

Relationships between Blood Pressure and Plasma Renin, Aldosterone and Dopamine-β-Hydroxylase in the Elderly

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