What do Cochrane systematic reviews say about new practices on integrative medicine?

Riera, Rachel; Braga, Vinícius Lopes; Rocha, Luana Pompeu dos Santos; Bernardo, Daniel Damasceno; Andrade, Luisa; Hsu, Jessica Chiu; Silva, Luciana Di Giovanni Marques da; Suetsugu, Rodrigo Cesar de Sá; Dittrich, Nicole; Lima, Lucas Riguete Pereira de; Silveira, Vicente Penido da; Kruglensky, Barbara Caon; Leonel, Letícia de Freitas; Barros, Edivando de Moura; Costa, Anderson Adriano Leal Freitas da; Quintella, Miguel Lins; Pacheco, Rafael Leite; Cruz, Carolina de Oliveira; Martimbianco, Ana Luiza Cabrera; Pachito, Daniela Vianna; Mozetic, Vânia; Teixeira, Tatiana de Bruyn Ferraz; Torloni, Maria Regina; Atallah, Álvaro Nagib

doi:10.1590/1516-3180.2018.0172170418

Cited by 5 publications

(1 citation statement)

References 20 publications

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“…Essa prática integrativa refere-se ao uso de subprodutos das abelhas (mel, apitoxinas ou própolis) para promoção da saúde ou como um tratamento de doenças. Além das propriedades biológicas dos méis já citadas neste trabalho, e que poderiam beneficiar os pacientes atendidos pelo SUS, outras atividades vinculadas, como por exemplo, o uso do mel para redução da tosse em crianças e veneno de abelha para prevenir reações alérgicas a picadas de insetos já são amplamente utilizadas em outros países 54 .…”

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Dentre as matérias primas extraídas da apicultura, o mel é considerado o produto mais fácil de ser explorado, sendo também aquele com maiores possibilidades de comercialização pois, além de ser um alimento, pode também ser utilizado na indústria farmacêutica e cosmética devido às suas conhecidas ações terapêuticas. Sabe-se que são diversas as propriedades medicinais dos méis, nesse sentido, essa revisão procurou avaliar a literatura científica da última década a respeito das propriedades biológicas associadas Brazilian Applied Science Review

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A methodological review finds mismatch between overall and pairwise overlap analysis in a sample of overviews

Bracchiglione,

Meza,

Pérez-Carrasco

et al. 2023

Journal of Clinical Epidemiology

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Antimicrobial activity of honey in periodontal disease: a systematic review

Hbibi

Sikkou²,

Khedid³

et al. 2020

Journal of Antimicrobial Chemotherapy

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Background Honey has shown positive antimicrobial and anti-inflammatory actions in several dermatological studies; however, it is unclear if it could be effective in the treatment of periodontal disease. Objectives To answer the question: Does honey have antimicrobial activity against periodontopathogens? Methods Six electronic databases were screened from initiation to 31 January 2019 for randomized clinical trials (RCTs) and controlled in vitro studies exploring the antimicrobial effect of honey against periodontopathogens. Honey’s botanical origin, periopathogens that showed microbial susceptibility to honey, MICs, microbial growth conditions, control product and clinical follow-up were the main investigated outcomes. The risk of bias (RoB) of included RCTs was assessed using the Cochrane Collaboration RoB tool. The RoB of in vitro studies was evaluated based on the Sarkis-Onofre judgement model adapted to the context of honey. Results A total of 1448 publications were found as search results in the screened databases. Sixteen eligible papers were included based on predetermined inclusion criteria. Retained studies included 5 RCTs and 11 in vitro controlled trials. Manuka and multifloral honeys were the most studied varieties. The tested honeys showed a significant antimicrobial action, with different MICs, against eight periopathogens. Four of the five RCTs showed a high RoB, while 4 of the 11 retained in vitro studies showed a medium RoB. Conclusions Honey showed a significant antimicrobial activity against all targeted periopathogens. Additional experiments are required to explore the entire antimicrobial spectrum of honey towards all pathogens involved in periodontal disease.

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What do Cochrane systematic reviews say about new practices on integrative medicine?

Abstract: Except for some specific uses of apitherapy (honey for burn wounds and for acute coughs and bee venom for allergic reactions to insect stings), the use of ten integrative practices that have recently been incorporated into SUS does not seem to be supported by evidence from Cochrane SRs.

Cited by 5 publications

References 20 publications

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A methodological review finds mismatch between overall and pairwise overlap analysis in a sample of overviews

Antimicrobial activity of honey in periodontal disease: a systematic review

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