What Can We Learn from the Allergic Zoo?

Weck, A.L. de

doi:10.1159/000236918

Cited by 21 publications

(5 citation statements)

References 10 publications

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“…House dust is also an important environmental allergen in humans and other animals [4,7], and is the most common allergen associated with canine AD [14,15]. However, there is no standardization for the production of house dust extract components among companies that manufacture allergens for laboratory purposes.…”

Section: Discussionmentioning

confidence: 99%

Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests

2011

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Intradermal tests were performed on 58 dogs diagnosed with atopic dermatitis from 2004~2008 at the Veterinary Medical Teaching Hospital of Konkuk University, Korea. To compare the allergen distribution observed in the present investigation to the results from other studies conducted in Korea and elsewhere, the allergens were grouped according to their kinds. There was no significant difference in gender distribution among the dogs. The most common breeds among the 58 dogs were Maltese (n = 11) and Shih-tzu (n = 11). The average age was 4.8 years. The most frequently produced a positive reaction on the intradermal tests was mold (67.3%) followed by house dust (54.5%) and house dust mites (49.1%). The present study found a low distribution of dogs allergic to various outdoor allergens compared to studies performed in other countries; this may reflect differences in living conditions for dogs living in Korea.

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Section: Discussionmentioning

confidence: 99%

Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests

2011

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“…2 Similarly, in dogs, there is no clear evidence that atopic dermatitis is inherited, although a strong breed predilection has been reported in Labrador and Golden Retrievers. 3,4 In addition, results of a breeding study by Schwartzman 5 indicated that certain charac-teristics of atopic disease were seen in the offspring of atopic parents, and de Weck 6 reported that Beagles could be classified as either high or low IgE responders and demonstrated that IgE concentrations were controlled by genetics.…”

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Estimation of heritability of atopic dermatitis in Labrador and Golden Retrievers

Shaw¹,

Wood²,

Freeman³

et al. 2004

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“…In recent years, the number of patients with allergic diseases has been increasing in dogs as well as in humans [2,5,7,10,20]. Immunogloblin E (IgE) antibodies play an important role in the development of immediate hypersensitivity (type I allergic disease) [7,10,20].…”

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confidence: 99%

Determination of Antigenic Proteins of Housedust Mites in 90 Dogs Suffering from Atopic Dermatitis.

Yamashita

Fujiwara

R³

et al. 2002

The Journal of Veterinary Medical Science

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ABSTRACT. Housedust mites, Dermatophagoides pteronyssinus (D. pteronyssinus) and Dermatophagoides farinae (D. farinae), are the important causative agents of allergic diseases in human and animals. By using 165 dogs suffering from atopic dermatitis (AD), serum levels of immunogloblin E (IgE) antibody against 25 kinds of allergen including housedust mites were determined. Housedust mites were the most frequent allergen against which 90 of the 165 allergic dogs (54.5%) by IMMUNODOT assay. With the further analysis of immunoblotting assay in the 90 dogs sensitized with housedust mites, antigenic proteins of housedust mites recognized by IgE antibodies were with the apparent molecular masses of 15, 76, 90, 98, and 170-kD. Among them, the 15-kD protein that might be ident ical to Group 2 antigens (Der f2, Der p2) was prominently observed (52/90). This study indicates that about a half of dogs with AD were sensitized to housedust mites, suggesting that Group 2 antigens of housedust mites may be a major allergen in canine AD. KEY WORDS: allergen, atopic dermatitis, canine, housedust mite, IgE.

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What Can We Learn from the Allergic Zoo?

Abstract: Several animal species, in particular dogs, cats and horses spontaneously develop IgE-mediated allergic diseases. They can also be experimentally sensitized. Comparative veterinary allergology is increasingly providing valuable information in allergy research.

Cited by 21 publications

References 10 publications

Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests

Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests

Estimation of heritability of atopic dermatitis in Labrador and Golden Retrievers

Determination of Antigenic Proteins of Housedust Mites in 90 Dogs Suffering from Atopic Dermatitis.

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