What Are the Needs for Transplantation Treatment in Vitiligo, and How Good Is It?

Treatment of vitiligo in children and adolescents by autologous cultured pure melanocytes transplantation with comparison of efficacy to results in adults

“…Transplantations of melanocytes are well‐established methods and must be considered to have low risk of side‐effects. In the light of the difficulties to achieve good results with pharmacological treatments in many patients and the individuals’ great concerns about the loss of the melanocytes, melanocyte transplantation must be considered as an important repigmentation procedure 27 …”

Modified procedure of noncultured epidermal suspension transplantation: Changes are the core of vitiligo surgery

“…Since there is a concern about the risk of prion disease with the use of collagen which is of bovine origin, we tried an alternate option where a sterile gauze smeared with the placental extract gel was used instead of a collagen sheet. [8] We found out that both achieved a comparable outcome. We used the placental extract gel to achieve a ‘moist wound healing’; we believe that any plain gel or even a gauze soaked in PBS could also be other alternative.…”

Treatment of vitiligo with khellin liposomes, ultraviolet light and blister roof transplantation

“…Unfortunately, in many patients refractory areas may remain, particularly on the distal body sites such as the dorsal parts of the hands and the feet, but all body sites may be involved. Photo‐medical treatment such as PUVA and KLUV may be efficacious where aforementioned treatment methods have failed 16,19,20,25 . It seems rational to prefer KLUV because khellin combines phototherapeutic properties that are similar to those of the psoralens 20 with substantially lower phototoxic and mutagenic effects 14,15 .…”

“…In stable vitiligo (such as segmental unilateral vitiligo) the outcome of transplantation therapy is usually excellent. In some cases, transplantation may indeed be the only effective treatment 25 . Unfortunately, to date there is no reliable test to predict the activity and the outcome of melanocyte transplantation treatment in patients with vitiligo.…”

“…Unfortunately, to date there is no reliable test to predict the activity and the outcome of melanocyte transplantation treatment in patients with vitiligo. Vitiligo can be active in one skin area and inactive or even in regression in another area at the same time 25 . Thus, it may be difficult to draw conclusions from patient’s anamnesis and from performing a few test grafts prior to more extensive treatments as an approach to predict stability.…”