Weiser-Maples strain of guinea-pigs

Jones, Lloyd D.; Weiser, O. L.

doi:10.1258/002367769781071916

Lab Anim

1969

DOI: 10.1258/002367769781071916

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Weiser-Maples strain of guinea-pigs

Lloyd D. Jones

O. L. Weiser

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Cited by 3 publications

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“…The colony has since reached its 20th generation (Inaba & Wakisaka 1992). Weiser-Maples guineapigs have been characterized as having a markedly uniform response to experimental tuberculosis (Jones & Weiser 1969). Their skin melanocytes have radial and vertical growth patterns similar to malignant melanomas in humans (Kligman & Elenitsas 2001), thereby making them available for use in skin melanization research including long-term studies of skin melanoma (Epstein 1992).…”

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Age-related changes in haematology and serum chemistry of Weiser–Maples guineapigs (Cavia porcellus)

et al. 2005

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SummaryAge-related changes in haematology and serum chemistry values were examined in male and female Weiser-Maples guineapigs (Cavia porcellus). Haematological changes that significantly (Po0.01) correlated with ageing were increased white blood cell and neutrophil counts in both sexes, decreased lymphocyte counts in both sexes, decreased reticulocyte and platelet counts in males, and decreased basophil counts in females. For serum chemistry, increases in total protein, triglycerides, blood urea nitrogen and creatinine were seen in both sexes, along with increases in total cholesterol in males and sodium in females. Decreased alkaline phosphatase in both sexes and decreased chloride in males were significantly (Po0.01) associated with age. These age-related changes are compared with the published literature.

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confidence: 99%

Age-related changes in haematology and serum chemistry of Weiser–Maples guineapigs (Cavia porcellus)

et al. 2005

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A Reproductive Study of Weiser-Maples Guinea Pigs

Inaba

Wakisaka

1992

Experimental Animals

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A Biological Study of Inbred Weiser-Maples Guinea Pigs

Yoshihara

Watanabe

Inaba

et al. 1994

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Urinalysis, hematological and blood chemical examinations and measurement of organ weights were carried out for the purpose of collecting background data on Weiser-Maples (WM) which was established as an inbred strain of guinea pigs. The results were compared with those for the commercial guinea pigs, Std: Hartley (H). In addition, the measurement methods for urinary specific gravity and whether centrifugation of urine influences the results of urinalysis or not were examined. The specific gravity values calculated from the volume and weight of urine were highly correlated with those from the refraction rate. The results of urinalysis of the supernatant of centrifuged urine were similar to those of urine not centrifuged, but the results suggested that the use of the supernatant provided a more accurate measurement of urine in guinea pigs. The positive rate for urinary protein was higher in the WM strain (38.9%) than in the H strain (0%). Although the WM strain showed higher or lower values than the H strain in some items of hematological and blood chemical examinations and organ weights, we could not regard them as characteristic of the WM strain. -KEY WORDS: biochemistry, hematology , inbred strain, urinalysis, Weiser-Maples guinea pig

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Weiser-Maples strain of guinea-pigs

Cited by 3 publications

References 2 publications

Age-related changes in haematology and serum chemistry of Weiser–Maples guineapigs (Cavia porcellus)

Age-related changes in haematology and serum chemistry of Weiser–Maples guineapigs (Cavia porcellus)

A Reproductive Study of Weiser-Maples Guinea Pigs

A Biological Study of Inbred Weiser-Maples Guinea Pigs

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