2014
DOI: 10.1007/s11695-014-1300-4
|View full text |Cite
|
Sign up to set email alerts
|

Weight Loss Associated with Bariatric Surgery Does Not Restore Short Telomere Length of Severe Obese Patients After 1 Year

Abstract: These results confirm that obese subjects have shorter telomeres compared to non-obese subjects, but RTL is not influenced by the presence of metabolic syndrome. RTL shows an additional attrition during the immediate post-operative period, probably due to a catabolic state.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
29
1

Year Published

2015
2015
2021
2021

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 25 publications
(32 citation statements)
references
References 30 publications
2
29
1
Order By: Relevance
“…Of these, one study found a positive relationship, in women with systemic lupus erythematosus . The other 38 studies found an inverse relationship . Among these articles, BMI was the most used method to assess obesity; only one study used WC and the adipocytes diameter as a main outcome variable instead of BMI.…”
Section: Resultsmentioning
confidence: 99%
“…Of these, one study found a positive relationship, in women with systemic lupus erythematosus . The other 38 studies found an inverse relationship . Among these articles, BMI was the most used method to assess obesity; only one study used WC and the adipocytes diameter as a main outcome variable instead of BMI.…”
Section: Resultsmentioning
confidence: 99%
“…Corroborating the former, restored telomere length among overweight and obese individuals has been suggested following specific weight loss interventions, including bariatric surgery [33] and bioenteric intragastric balloon (BIB) in adults [34], and lifestyle modification in adolescents [35]. Nevertheless, a positive association between weight loss and LTL was observed among BIB but not bariatric surgery patients [33, 34, 36] and no alteration of telomere length was observed following lifestyle modification in adults [37, 38]. Except one study which followed the participants until 10 years after undergoing bariatric surgery [33], these previous findings had relatively short-term follow-up (6 months to 4.5 years), which may have limited the sensitivity in observing changes secondary to weight loss.…”
Section: Discussionmentioning
confidence: 99%
“…However, they also saw significant methodological, clinical, and statistical heterogeneity between studies, which suggests that this association needs to be better defined and additional causative factors must be taken into account [59]. The effect of intentional weight loss on telomere length has been studied in two RCTs and two non-randomized intervention studies (table 3) [8,9,60,61]. …”
Section: Resultsmentioning
confidence: 99%