Weed resistance to synthetic auxin herbicides

Busi, Roberto; Goggin, Danica E.; Heap, Ian; Horak, Michael J.; Jugulam, Mithila; Masters, Robert A.; Napier, Richard; Riar, Dilpreet S.; Satchivi, Norbert M.; Torra, Joel; Westra, Philip; Wright, Terry R.

doi:10.1002/ps.4823

Cited by 138 publications

(167 citation statements)

References 72 publications

Supporting

Mentioning

147

Contrasting

Unclassified

Order By: Relevance

“…In the case of 2,4-D, the accumulation of ethylene was evidenced in the R and S plants treated with 2,4-D and has been reported by several authors [38,42,[69][70][71]. The lower accumulation of ethylene in R plants may be due to the herbicide not reaching its nuclear protein receptor complex to suppress the genes responsible for ethylene production, which respond to auxins [71][72][73]. Susceptible plants exposed to 2,4-D die due to unregulated auxin activity and the accumulation of reactive oxygen species (ROS), ABA, and ethylene [72,74].…”

Section: Discussionsupporting

confidence: 75%

Evolving Multiple Resistance to EPSPS, GS, ALS, PSI, PPO, and Synthetic Auxin Herbicides in Dominican Republic Parthenium hysterophorus Populations. A Physiological and Biochemical Study

et al. 2020

View full text Add to dashboard Cite

Two Parthenium hysterophorus populations resistant (R) and susceptible (S) harvested in banana crop from the Dominican Republic were studied. All S plants died when the herbicides were applied at field dose, except with paraquat. For the R population, the order of plant survival was as follows: glyphosate and paraquat > flazasulfuron > glufosinate > fomesafen > 2,4-D. The resistance factors obtained in the dose–response assays showed a high resistance to glyphosate, flazasulfuron, and fomesafen, medium resistance to glufosinate and 2,4-D, and a natural tolerance to paraquat (resistance factor (RF) = 1.0). The I50 values obtained in the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), acetolactate synthase (ALS), and glutamine synthetase (GS) activity studies with glyphosate, flazasulfuron, and glufosinate, respectively, were greater in R than in S. The effect of fomesafen was measured by the Proto IX levels, obtaining five times more Proto IX in the S than in the R population. The resistance to 2,4-D in the R was determined by the lower accumulation of ethylene compared to the S population. The studies with 14C-paraquat conclude that the lower absorption and translocation in both the R and S populations would explain the natural tolerance of P. hysterophorus. This is the first case of multiple resistance to herbicides with different mechanisms of action confirmed in P. hysterophorus.

show abstract

Section: Discussionsupporting

confidence: 75%

Evolving Multiple Resistance to EPSPS, GS, ALS, PSI, PPO, and Synthetic Auxin Herbicides in Dominican Republic Parthenium hysterophorus Populations. A Physiological and Biochemical Study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Group A herbicides or acetyl-CoA carboxylase (ACCase) inhibitors were first introduced into the market in 1978 (Kaundun, 2014) with the appearance of diclofop-methyl. These herbicides provide selective grass weed control in dicot crops and a limited number of active ingredients for use in monocot crops with an estimated treated area of 120 million ha per year (Busi et al, 2018). ACCase-inhibiting herbicides play a key role in managing glyphosate-resistant (GR) grasses, one of the greatest weed management challenges facing South America (Lopez Ovejero et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

ACCase-inhibiting herbicides: mechanism of action, resistance evolution and stewardship

Takano

Ovejero

Belchior³

et al. 2021

Sci. agric. (Piracicaba, Braz.)

View full text Add to dashboard Cite

Herbicides play an important role in preventing crop yield losses due to both their weed interference ability and their capacity for increasing soil conservation in no-till systems. Group A herbicides or acetyl-CoA carboxylase (ACCase) are essential tools the selective management of glyphosate resistance in grass weed species. In this review, we describe important aspects of ACCase biology and herbicides targeting this enzyme, along with a discussion on stewardship programs to delay the evolution of herbicide resistance which can evolve either through target site and/or non-target site mechanisms. Sixteen-point mutations have been reported to confer resistance to ACCase inhibitors. Each mutation confers cross resistance to a different group of herbicides. Metabolic resistance can result in resistance to multiple herbicides with different mechanisms of action (MoA), and herbicide detoxification is often conferred by cytochrome P450 monooxigenases and glutathione-Stransferases. Regardless of whether resistance mechanisms are target or non-target site, using herbicides with the same MoA will result in resistance evolution. Therefore, while field surveys and resistance mechanism studies are crucial for designing reactive management strategies, integrated weed management plays a central role in both reactive and proactive mitigation of herbicide resistance evolution.

show abstract

“…Additionally, a few weeds have already developed resistance to picloram (Busi et al , ). While the exact genetic basis of resistance in these weeds is not yet known, it is possible that picloram resistance of at least some of these weeds may be due to defects in picloram uptake and transport, as the case in pic30 mutants.…”

Section: Discussionmentioning

confidence: 99%

Arabidopsis PIC30 encodes a major facilitator superfamily transporter responsible for the uptake of picolinate herbicides

et al. 2020

View full text Add to dashboard Cite

Picloram is an auxinic herbicide that is widely used for controlling broad leaf weeds. However, its mechanism of transport into plants is poorly understood. In a genetic screen for picloram resistance, we identified three Arabidopsis mutant alleles of PIC30 (PICLORAM RESISTANT30) that are specifically resistant to picolinates, but not to other auxins. PIC30 is a previously uncharacterized gene that encodes a major facilitator superfamily (MFS) transporter. Similar to most members of MFS, PIC30 contains 12 putative transmembrane domains, and PIC30-GFP fusion protein selectively localizes to the plasma membrane. In planta transport assays demonstrate that PIC30 specifically transports picloram, but not indole-3-acetic acid (IAA). Functional analysis of Xenopus laevis oocytes injected with PIC30 cRNA demonstrated PIC30 mediated transport of picloram and several anions, including nitrate and chloride. Consistent with these roles of PIC30, three allelic pic30 mutants are selectively insensitive to picolinate herbicides, while pic30-3 is also defective in chlorate (analogue of nitrate) transport and also shows reduced uptake of 15 NO À 3 . Overexpression of PIC30 fully complements both picloram and chlorate insensitive phenotypes of pic30-3. Despite the continued use of picloram as an herbicide, a transporter for picloram was not known until now. This work provides insight into the mechanisms of plant resistance to picolinate herbicides and also shed light on the possible endogenous function of PIC30 protein.

show abstract

Weed resistance to synthetic auxin herbicides

Cited by 138 publications

References 72 publications

Evolving Multiple Resistance to EPSPS, GS, ALS, PSI, PPO, and Synthetic Auxin Herbicides in Dominican Republic Parthenium hysterophorus Populations. A Physiological and Biochemical Study

Evolving Multiple Resistance to EPSPS, GS, ALS, PSI, PPO, and Synthetic Auxin Herbicides in Dominican Republic Parthenium hysterophorus Populations. A Physiological and Biochemical Study

ACCase-inhibiting herbicides: mechanism of action, resistance evolution and stewardship

Arabidopsis PIC30 encodes a major facilitator superfamily transporter responsible for the uptake of picolinate herbicides

Contact Info

Product

Resources

About