WEB Treatment of Intracranial Aneurysms: Feasibility, Complications, and 1-Month Safety Results with the WEB DL and WEB SL/SLS in the French Observatory

Abstract

BACKGROUND AND PURPOSE:Safety analyses in the French Observatory have shown that treatment of intracranial aneurysms by using flow disruption with the Woven EndoBridge Device (WEB) is safe, with low morbidity and no mortality. The objective of this study was to analyze treatment feasibility, complications, and safety results in patients treated with the Woven EndoBridge Device Dual-Layer (WEB DL) and Woven EndoBridge Device Single-Layer/Single-Layer Sphere (WEB SL/SLS) in the French Observatory.

WEB Treatment of Intracranial Aneurysms: Clinical and Anatomic Results in the French Observatory

“…[10][11][12][13][14][15][16][17] The rate of thromboembolic events with the WEB (14.5%) was quite similar to that reported in the Analysis of Treatment by Endovascular Approach of Nonruptured Aneurysms (ATENA) and Clinical and Anatomical Results In the Treatment of Ruptured Intracranial Aneurysms (CLARITY) series (respectively, 7.3% and 13.3%).…”

“…The short-term (6-month) results of the WEBCAST trial and a comparison of safety between the WEB DL and WEB SL/SLS in the French Observatory were published previously. 16,17 These initial analyses confirmed the good safety and efficacy of the device in the short-term. This article reports the clinical and anatomic results of the French Observatory study with midterm (1-year) follow-up.…”

“…Previous analyses showed a similar safety of treatment with the devices, with a trend toward less thromboembolic events in patients treated with Single-Layer devices. 16 Anatomically, results were similar in both groups of patients, with complete occlusion in 50.0% of patients treated with WEB DL, 53.3% of patients treated with WEB SL/ SLS, and adequate occlusion in, respectively, 78.6% and 80.0%.…”

“…16 Briefly, inclusion criteria were ruptured (Hunt and Hess 1, 2, or 3), unruptured, and recanalized bifurcation aneurysms located in the basilar artery, middle cerebral artery, anterior communicating artery, and internal carotid artery terminus. In each center, the indication for endovascular treatment was decided by a local multidisciplinary team, which included neurosurgeons and neuroradiologists.…”

Evaluation of the Angiographic Grading Scale in Aneurysms Treated with the WEB Device in 80 Rabbits: Correlation with Histologic Evaluation

“…Initial experimental and clinical studies have demonstrated that the WEB is both safe and effective in the treatment of intracranial aneurysms. [1][2][3][4][5][6][7][8][9] Because the mechanism of action of the device differs from that in flow diverters and endosaccular coils, developing tools to assess angiographic occlusion has become a recent priority among many neurointerventionists, and several grading scales have been proposed. 4,[7][8][9][10] Perhaps the most commonly used scale is the WEB Occlusion Scale (WOS).…”