Wear simulation of a polyethylene-on-metal cervical total disc replacement under different concentrations of bovine serum lubricant

Hyde, PJ; Fisher, John; Hall, Richard M.

doi:10.1177/0954411915602914

Cited by 9 publications

(4 citation statements)

References 26 publications

(37 reference statements)

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“…For UHMWPE-on-cobalt chrome at both standard rig running and elevated temperatures, there was a trend of increasing wear factor with increasing protein concentration. These findings corroborate with those of several previous pin-on-plate (Galvin, 2003) and whole joint wear simulation studies (Good et al, 2000, Hyde et al, 2016) run at room temperature however, other studies also carried out at room temperature have reported an inverse relationship between protein concentration and wear (Liao et al, 1999, Liao et al, 2003, Muratoglu et al, 2004). Differences in simulation systems and test protocols, and the use of additives such as EDTA and antibiotics to the lubricant may have contributed to the different test outcomes.…”

Section: Discussionsupporting

confidence: 91%

Wear and Friction of UHMWPE-on-PEEK OPTIMA™

Cowie

Briscoe²,

Fisher

et al. 2019

Journal of the Mechanical Behavior of Biomedical Materials

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PEEK-OPTIMA™ is being considered as an alternative bearing material to cobalt chrome in the femoral component of total knee replacement to provide a metal-free implant. The aim of this study was to investigate the influence of lubricant temperature (standard rig running and elevated temperature (~36 °C)) on the wear of a UHMWPE-on-PEEK OPTIMA™ bearing couple using different lubricant protein concentrations (0%, 2%, 5%, 25% and 90% bovine serum) in a simple geometry pin-on-plate configuration. Friction was also investigated under a single temperature condition for different lubricant protein concentrations. The studies were repeated for UHMWPE-on-cobalt chrome in order to compare relationships with temperature (wear only) and lubricant protein concentration (wear and friction). In low lubricant protein concentrations (≤ 5%) there was no influence of temperature on the wear factors of UHMWPE-on-PEEK. With 25% bovine serum, the wear factor of UHMWPE-on-PEEK reduced by half at elevated temperature. When tested in high protein concentration (90% serum), there was no influence of temperature on the wear factor of UHMWPE-on-PEEK. These temperature dependencies were not the same for UHMWPE-on-cobalt chrome. For both material combinations, there was a trend of decreasing friction with increasing protein concentration once protein was present in the lubricant. This study has shown the importance of the selection of appropriate test conditions when investigating the wear and friction of different materials, in order to minimise test artefacts such as polymer transfer, and protein precipitation and deposition.

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Section: Discussionsupporting

confidence: 91%

Wear and Friction of UHMWPE-on-PEEK OPTIMA™

Cowie

Briscoe²,

Fisher

et al. 2019

Journal of the Mechanical Behavior of Biomedical Materials

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“…The wear rate was shown to be proportional to the total protein content of the BCS (Hyde et al , 2016). Analogously, it was found that the wear loss of UHMWPE pin specimens increased with a concentration in both BSA and BSG ( p ≤ 0.05) (Figure 4), whereas the pin wear was almost negligible in the protein-free lubricants, such as DPPC, HA and PBS.…”

Section: Resultsmentioning

confidence: 99%

Effect of synovial fluid constituent on the tribological behaviors of UHMWPE-CoCrMo alloy contact pair

Tan

Zhang

et al. 2023

ILT

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Purpose This study aims to systematically investigate the tribological behaviors of metal and polyethylene using lubricants composed of four synovial fluid (SF) components. In addition, the changes in protein conformation during wear were analyzed to establish the correlation between protein conformation and tribological properties. Design/methodology/approach A pin-on-disk tester with multidirectional sliding motion was used for tribological properties observation between metal and polyethylene pairs. Simulated SFs with four main constituents were used as the testing lubricants. Differential scanning calorimetry and Raman were used to characterize the changes in protein conformation during wear. Findings The coupling of lipids and hyaluronic acid further suppressed protein denaturation. The protein structures of the adsorption film and the ensnared protein chains in the friction zone were maintained to a certain extent, thus improving the friction and wear of polyethylene. Originality/value These findings established the correlation between protein conformation and friction and wear, promoting the understanding of the lubrication mechanism of artificial joints.

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“…We used the Institute of Biomechanics of Valencia spine wear stimulator, complying with ISO 18192-1 standard [ 14 ] (Figure S2S, supplementary material). This machine has basins to submerge the TDR samples during the test in a BS solution with a protein content similar to the human synovial fluid [ 15 , 16 ], penicillin, amphotericin, and EDTA and kept at 37 ± 2 °C.…”

Section: Methodsmentioning

confidence: 99%