Wear Resistance, Cytotoxicity and Antibacterial Properties of Polyetheretherketone Composite Modified by Carbon Fiber and Black Phosphorus

Li, Jingdan; Liang, Qian; Qin, Wen; Ma, Jing

doi:10.1007/s42235-021-00121-9

Cited by 6 publications

(4 citation statements)

References 55 publications

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“…Recent research by Li et al has shown that a polyetheretherketone composite modified with black phosphorus and carbon fiber shows superior wear resistance, minimal cytotoxicity, and exceptional antimicrobial properties. These findings suggest that this composite could be an ideal material for implants ( Li J. et al, 2022 ).…”

Section: Current Developments Of Nanotechnology In Orthopedic Implantsmentioning

confidence: 73%

Current developments and future perspectives of nanotechnology in orthopedic implants: an updated review

Liang,

Zhou,

Bai

et al. 2024

Front. Bioeng. Biotechnol.

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Orthopedic implants are the most commonly used fracture fixation devices for facilitating the growth and development of incipient bone and treating bone diseases and defects. However, most orthopedic implants suffer from various drawbacks and complications, including bacterial adhesion, poor cell proliferation, and limited resistance to corrosion. One of the major drawbacks of currently available orthopedic implants is their inadequate osseointegration at the tissue-implant interface. This leads to loosening as a result of immunological rejection, wear debris formation, low mechanical fixation, and implant-related infections. Nanotechnology holds the promise to offer a wide range of innovative technologies for use in translational orthopedic research. Nanomaterials have great potential for use in orthopedic applications due to their exceptional tribological qualities, high resistance to wear and tear, ability to maintain drug release, capacity for osseointegration, and capability to regenerate tissue. Furthermore, nanostructured materials possess the ability to mimic the features and hierarchical structure of native bones. They facilitate cell proliferation, decrease the rate of infection, and prevent biofilm formation, among other diverse functions. The emergence of nanostructured polymers, metals, ceramics, and carbon materials has enabled novel approaches in orthopaedic research. This review provides a concise overview of nanotechnology-based biomaterials utilized in orthopedics, encompassing metallic and nonmetallic nanomaterials. A further overview is provided regarding the biomedical applications of nanotechnology-based biomaterials, including their application in orthopedics for drug delivery systems and bone tissue engineering to facilitate scaffold preparation, surface modification of implantable materials to improve their osteointegration properties, and treatment of musculoskeletal infections. Hence, this review article offers a contemporary overview of the current applications of nanotechnology in orthopedic implants and bone tissue engineering, as well as its prospective future applications.

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Section: Current Developments Of Nanotechnology In Orthopedic Implantsmentioning

confidence: 73%

Current developments and future perspectives of nanotechnology in orthopedic implants: an updated review

Liang,

Zhou,

Bai

et al. 2024

Front. Bioeng. Biotechnol.

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“…BP has low cytotoxicity, and the 1 O 2 it produces can destroy the bacterial membrane of S. aureus, significantly improving the antibacterial performance of the polymer. 129 Li et al 130 deposited BP on the surface of carbon fiber reinforced (CFR)-PEEK. Mechanical experiment results showed that the abrasion resistance of modified PEEK is improved effectively, which may be due to the coating not being easy to oxidize.…”

Section: Copper Coatingsmentioning

confidence: 99%

“…Li et al 130 deposited BP on the surface of carbon fiber reinforced (CFR)-PEEK. Mechanical experiment results showed that the abrasion resistance of modified PEEK is improved effectively, which may be due to the coating not being easy to oxidize.…”

Section: Surface Modification Substance Coatingsmentioning

confidence: 99%

Multifaceted Materials for Enhanced Osteogenesis and Antimicrobial Properties on Bioplastic Polyetheretherketone Surfaces: A Review

Bai,

Zhao,

Cui

et al. 2024

ACS Omega

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Implant-associated infections and the increasing number of bone implants loosening and falling off after implantation have become urgent global challenges, hence the need for intelligent alternative solutions to combat implant loosening and falling off. The application of polyetheretherketone (PEEK) in biomedical and medical therapy has aroused great interest, especially because its elastic modulus close to bone provides an effective alternative to titanium implants, thereby preventing the possibility of bone implants loosening and falling off due to the mismatch of elastic modulus. In this Review, we provide a comprehensive overview of recent advances in surface modifications to prevent bone binding deficiency and bacterial infection after implantation of bone implants, starting with inorganics for surface modification, followed by organics that can effectively promote bone integration and antimicrobial action. In addition, surface modifications derived from cells and related products of biological activity have been proposed, and there is increasing evidence of clinical potential. Finally, the advantages and future challenges of surface strategies against medical associated poor osseointegration and infection are discussed, with promising prospects for developing novel osseointegration and antimicrobial PEEK materials.

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“…Recently, Li et al have shown that a polyetheretherketone composite modified by carbon fiber and black phosphorus exhibited higher wear resistance, low cytotoxicity, and magnificent antimicrobial properties against S. aureus, thus making it a suitable composite for implant material . A similar study was also conducted by Sun et al where the group demonstrated that a composite made of polyetheretherketone (PEEK)/polytetrafluoroethylene (PTFE) with black phosphorus (BP) nanosheets was able to increase the wear resistance and antimicrobial property while being much less cytotoxic .…”

Section: D-nanomaterial-based Nanocoatingmentioning

confidence: 99%

Nanomaterial-Based Antimicrobial Coating for Biomedical Implants: New Age Solution for Biofilm-Associated Infections

et al. 2022

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Recently, the upsurge in hospital-acquired diseases has put global health at risk. Biomedical implants being the primary source of contamination, the development of biomedical implants with antimicrobial coatings has attracted the attention of a large group of researchers from around the globe. Bacteria develops biofilms on the surface of implants, making it challenging to eradicate them with the standard approach of administering antibiotics. A further issue of current concern is the fast resurgence of resistance to conventional antibiotics. As nanotechnology continues to advance, various types of nanomaterials have been created, including 2D nanoparticles and metal and metal oxide nanoparticles with antimicrobial properties. Researchers from all over the world are using these materials as a coating agent for biomedical implants to create an antimicrobial environment. This comprehensive and contemporary review summarizes various metals, metal oxide nanoparticles, 2D nanomaterials, and their composites that have been used or may be used in the future as an antimicrobial coating agent for biomedical implants, as well as their succinct mode of action to combat biofilm-associated infection and diseases.

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Wear Resistance, Cytotoxicity and Antibacterial Properties of Polyetheretherketone Composite Modified by Carbon Fiber and Black Phosphorus

Cited by 6 publications

References 55 publications

Current developments and future perspectives of nanotechnology in orthopedic implants: an updated review

Current developments and future perspectives of nanotechnology in orthopedic implants: an updated review

Multifaceted Materials for Enhanced Osteogenesis and Antimicrobial Properties on Bioplastic Polyetheretherketone Surfaces: A Review

Nanomaterial-Based Antimicrobial Coating for Biomedical Implants: New Age Solution for Biofilm-Associated Infections

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