Wear and Tear Vision

Weber, Konrad P.; Schweier, Caterina; Kana, Veronika; Guggi, Thomas; Byber, Katarzyna; Landau, Klara

doi:10.1097/wno.0000000000000200

Cited by 7 publications

(4 citation statements)

References 12 publications

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“…This corresponds to the results of the photopic full-field ERG, which showed markedly reduced responses in one of our patients. Because of the suspected cone dystrophy, as in similar case reports previously, cancer-associated retinopathy was considered in the differential diagnosis 8 . A fundus autofluorescence test was performed in only one of our patients (patient 4) and showed hyperfluorescence beneath the fovea bilaterally.…”

Section: Discussionmentioning

confidence: 94%

“…Dies entspricht den Ergebnissen des photopischen Ganzfeld-ERGs, das bei einem unserer Patienten deutlich reduzierte Antworten aufwies. Aufgrund der vermuteten Zapfendystrophie wurde wie bereits bei ähnlichen Fallberichten eine "cancerassociated retinopathy" differenzialdiagnostisch in Erwägung gezogen [8]. Eine Fundusautofluoreszenzuntersuchung (FAG-Unter- suchung) wurde nur bei einem unserer Patienten durchgeführt (Pat.…”

Section: Diskussionunclassified

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Opticopathy Caused by Endoprosthesis-Related Cobalt Intoxication

Bodenbender

Schubert

Paul

2021

Klin Monbl Augenheilkd

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Section: Discussionmentioning

confidence: 94%

Section: Diskussionunclassified

Opticopathy Caused by Endoprosthesis-Related Cobalt Intoxication

Bodenbender

Schubert

Paul

2021

Klin Monbl Augenheilkd

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“…Weber et al described a woman with a history of hip prosthesis and decreased vision OU with an ISCEV-standard full-field ERG showing significant cone dysfunction (6). Similarly, Apel et al reported a case of arthroprosthetic cobaltism with persistent abnormalities in all phases of ERG including a negative b-waveform, suggesting inner retinal pathology (4).…”

Section: Discussionmentioning

confidence: 99%

Cobalt–Chromium Metallosis With Normal Electroretinogram

Grillo

Nguyen

Tsang

et al. 2016

Journal of Neuro-Ophthalmology

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Background Ocular cobalt toxicity is a rare phenomenon reported with increased frequency due to the rise of cobalt-chromium metal hip implants. We report the case of a 66 year-old previously healthy man who developed decreased vision due to cobalt-chromium toxicity from a metal-on-metal hip arthroplasty. Our objective was to determine whether the origin of his visual loss was due to toxicity of the optic nerve, of the retina, or of both. Methods Ocular examination, 10–2 SITA-Standard Humphrey Visual Field (VF), standard full-field electroretinogram (ERG) as indicated by the International Society for Clinical Electrophysiology of Vision (ISCEV), multifocal electroretinogram (mfERG), multifocal visual evoked potentials (mfVEP), and optical coherence tomography (OCT) were conducted. Results Ocular examination revealed decreased visual acuity, poor color vision, normal funduscopy, and cecocentral scotomas on visual field. As his right eye was amblyopic since childhood, test results from only the left eye are shown. Electrophysiology studies revealed an ISCEV standard full-field ERG with photopic and scotopic responses within normal limits, mfERG with amplitudes and latencies within normal limits, and mfVEP with latencies within normal limits, but with decreased central amplitudes. Peripapillary and macular OCT showed retinal nerve fiber layer (RNFL) and retinal ganglion cell-inner plexiform layer (RGC-IPL) thickness within normal limits. Conclusion As decreased color vision and cecocentral scotoma on 10–2 VF are most consistent with toxic optic neuropathy, and decreased central amplitudes on mfVEP are suggestive of neural dysfunction, we hypothesize that our patient presented with an early stage of optic nerve toxicity that was not yet apparent as a structural abnormality on OCT.

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“…toxic (Chapter 4.1.3.1, ▶ Fig. 2) aminoglycosides (especially gentamicin and tobramycin), cisplatin, loop diuretics, salicylate in high doses (5g/d) [396], penicillin + non-steroidal anti-inflammatory drugs [397], amiodarone [398], hydroxychloroquine [399], styrene poisoning [400], chronic exposure to jet fuel [401], cobalt toxicosis (e.g., hip replacement) [402] metabolic kidney failure, vitamin-B1, -B6, -B12 or folic acid deficiency [403], hypothyroidism, diabetes mellitus [404] neoplastic neurofibromatosis type II [413], skull base meningiomas, carcinomatous meningitis, metastases / lymphoma in the cerebellopontine angle [414] others aseptic meningitis [415], vestibular atelectasis (Chapter 3.2.8, ▶ Fig. 8), presbyvestibulopathy [416], auditory neuropathy spectrum disorders, otosclerosis [417] [298, 332] (▶ Fig.…”

Section: Toxic and Metabolic Causes 41311 Aminoglycosidesmentioning

confidence: 99%

Seltene Erkrankungen des vestibulären Labyrinths: von Zebras, Chamäleons und Wölfen im Schafspelz

Dlugaiczyk

2021

Laryngorhinootologie

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ZusammenfassungDie Differenzialdiagnose von Erkrankungen des vestibulären Labyrinths stellt eine grosse Herausforderung dar, da sich hinter dem sehr häufigen Leitsymptom «Schwindel» viele verschiedene und v. a. seltene Erkrankungen verbergen können. Der vorliegende Beitrag gibt einen Überblick über die für den HNO-Arzt wichtigen seltenen Erkrankungen des vestibulären Labyrinths ausgehend von ihrer klinischen Präsentation als akutes (AVS), episodisches (EVS) oder chronisches vestibuläres Syndrom (CVS). Der Schwerpunkt liegt dabei auf den EVS, sortiert nach ihrer Dauer und dem Vorhandensein von Triggern (Sekunden, ohne Trigger: Vestibularisparoxysmie, Tumarkin-Krise; Sekunden, lärm- und druckinduziert: Syndrome des «dritten Fensters»; Sekunden bis Minuten, positionsabhängig: seltene Varianten und Differenzialdiagnosen des benignen paroxysmalen Lagerungsschwindels; Stunden bis Tage, spontan: intralabyrinthäre Schwannome, Tumoren des endolymphatischen Sacks, Autoimmunerkrankungen des Innenohres). Des Weiteren werden seltene Differenzialdiagnosen eines AVS (Neuritis vestibularis inf., Otolithenfunktionsstörungen, vaskuläre Ursachen, akute bilaterale Vestibulopathie) und eines CVS (bilaterale Vestibulopathie) erläutert. Dabei werden insbesondere die entscheidenden diagnostischen Massnahmen für die Identifikation der einzelnen Krankheitsbilder und die Warnzeichen für potentiell gefährliche Ursachen (z. B. Labyrinthinfarkt/-blutung) dargelegt. Somit dient dieser Beitrag dem HNO-Arzt in Klinik und Praxis als eine Art «Vademecum» für die zügige Identifikation und zeitnahe Therapie seltener Erkrankungen des Gleichgewichtsorgans.

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Wear and Tear Vision

Cited by 7 publications

References 12 publications

Opticopathy Caused by Endoprosthesis-Related Cobalt Intoxication

Opticopathy Caused by Endoprosthesis-Related Cobalt Intoxication

Cobalt–Chromium Metallosis With Normal Electroretinogram

Seltene Erkrankungen des vestibulären Labyrinths: von Zebras, Chamäleons und Wölfen im Schafspelz

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