Weakness is Associated with Time to Incident Chronic Heart Failure in Aging Americans

McGrath, Ryan; Lee, D.-C.; Kraemer, William J.; Vincent, Brenda M.; Shaughnessy, K. A.; Terbizan, Donna J.

doi:10.1007/s12603-019-1266-y

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…33 Another longitudinal-panel study of 17,431 Americans aged at least 50 years determined that those who were weak had a 1.35 higher hazard (p < 0.05) for developing chronic heart failure compared to persons who were not weak at 4.7 ± 2.7 years of follow-up. 34 Although there appears to be an association between HGS and cardiovascular disease, measures of HGS may also help to predict other prevalent chronic morbidities such as diabetes.…”

Section: Hgs and Chronic Cardiometabolic Morbiditiesmentioning

confidence: 99%

What are the association patterns between handgrip strength and adverse health conditions? A topical review

et al. 2020

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Measures of handgrip strength can be used to conveniently assess overall muscle strength capacity. Although stand-alone measures of handgrip strength provide robust health information, the clinical meaningfulness to determine prevention and treatment options for weakness remains limited because the etiology of muscle weakness remains unclear. Moreover, clinical outcomes associated with handgrip strength are wide-ranging. Therefore, disentangling how handgrip strength is associated with health conditions that are metabolically or neurologically driven may improve our understanding of the factors linked to handgrip strength. The purpose of this topical review was to highlight and summarize evidence examining the associations of handgrip strength with certain health outcomes that are metabolically and neurologically driven. From this perusal of the literature, we posit that stand-alone handgrip strength be considered an umbrella assessment of the body systems that contribute to strength capacity, and a panoptic measurement of muscle strength that is representative of overall health status, not a specific health condition. Recommendations for future strength capacity–related research are also provided.

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Section: Hgs and Chronic Cardiometabolic Morbiditiesmentioning

confidence: 99%

What are the association patterns between handgrip strength and adverse health conditions? A topical review

et al. 2020

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“…HGS is, by itself, deemed as a useful outcome predictor in HF, being associated with incidence [36], hospitalization [37] and mortality [38].…”

Section: Discussionmentioning

confidence: 99%

Frailty phenotype and associated nutritional factors in a sample of Portuguese outpatients with heart failure

Valdiviesso

Azevedo

Moreira

et al. 2021

Nutrition, Metabolism and Cardiovascular Diseases

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Background and aim: Frailty phenotype (FP) is very common in heart failure (HF) and both syndromes worsen one another. The aim of this study is to first describe FP in a sample of Portuguese patients with HF, and to analyse its association with nutritional and clinical statuses, namely, muscle mass, obesity and functional class. Methods and results: In this cross-sectional study, a sample of 136 outpatients with HF (24e81 years, 33.8% women) were randomly selected from the appointments' listings of a HF and Transplant clinic in a Portuguese University Hospital. FP was assessed according to Fried et al. muscle mass was estimated from the mid-upper arm muscle circumference; weight status was assessed using the body mass index; HF functional classes were registered. The association between participants' characteristics and FP categories was analysed using logistic ordinal regression. The frequency of pre-frailty and frailty is 57.4% and 15.4%, respectively. Within frail individuals, 52.4% were under the age of 65. In multivariable analysis, frailty was positively associated with age 70 or older (OR Z 3.44) and obesity (OR Z 2.66), and negatively associated with muscle mass (OR Z 0.77) and HF functional classes I (OR Z 0.14) or II (OR Z 0.29). Conclusion: Muscle mass seems to be an important predictor of frailty in patients with HF and should be taken into account when designing intervention plans that allow for reverting or modifying frailty and pre-frailty. Younger patients should be monitored for the presence and evolution of FP.

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The causal relationship between sarcopenia-related traits and ECG indices - A mendelian randomization study

Fu,

Yu,

Liu

et al. 2024

Archives of Gerontology and Geriatrics

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Weakness is Associated with Time to Incident Chronic Heart Failure in Aging Americans

Cited by 5 publications

References 19 publications

What are the association patterns between handgrip strength and adverse health conditions? A topical review

What are the association patterns between handgrip strength and adverse health conditions? A topical review

Frailty phenotype and associated nutritional factors in a sample of Portuguese outpatients with heart failure

The causal relationship between sarcopenia-related traits and ECG indices - A mendelian randomization study

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