Water-soluble optical sensors: keys to detect aluminium in biological environment

Abstract

Aluminium ion plays a critical role in cellular health. Therefore, its detection in water is highly demanding.

Ru(ii) catalyzed chelation assisted C(sp2)–H bond functionalization along with concomitant (4 + 2) annulation

“…On the basis of environmental impact, the detection of Al 3+ ions is very essential because it is a major pollutant and has damaged our environment through a number of anthropogenic activities and its toxicity hinders not only plant growth but also the human nervous system, which can further lead to dementia, Alzheimer's disease, Parkinson's disease etc. 21 Now among the available detection methods (AMS, GFAAS, AAS, ICP-AAS, IC-AES etc .) the spectrofluorimetric method is superior to those traditional methods due to its high sensitivity, selectivity and operational simplicity.…”

Review on Lysosomal Metal Ion Detection Using Fluorescent Probes

“…In 2022, Guo and co-workers designed and synthesized a pHtolerant rhodamine-based Fe(III) sensor (5) with an Fe(III) binding moiety (Figure 4). 11 Upon introduction of Fe(III), compound 5 exhibited increase in absorption at 555 nm, accompanied by a turn-on fluorescence response with emission maximum at 580 nm in acetonitrile/Tris-HCl buffer (10 mM, pH 7.3, v/v 3:1).…”

Trivalent metal ion sensor enabled bioimaging and quantification of vaccine-deposited Al3+in lysosomes

“…27 To date, ample fluorescent indicators, including metalorganic frameworks (MOFs), small organic molecules, and nanoparticles, have been recognized for metal ion sensing. [28][29][30][31][32][33] Small fluorogenic probes have dominated over other chemosensors because of their facile synthesis and detection methods. [34][35][36][37][38][39][40][41][42][43] According to the HSAB principle, chemosensors bearing hard bases such as oxygen (O) and nitrogen (N) on their coordination sites can efficiently chelate with hard acids such as trivalent metal cations (M 3+ ).…”