Water-solubility of chitosan and its antimicrobial activity

Qin, Caiqin; Li, Huirong; Xiao, Qi; Liu, Yi; Zhu, Jiangfeng; Du, Yumin

doi:10.1016/j.carbpol.2005.09.023

Cited by 593 publications

(311 citation statements)

References 36 publications

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“…(ii) The composite showed higher thermal stability than chitosan which is beneficiary for the application of chitosan/clay composite in different purposes. (iii) Pure chitosan gets dissolved in acidic media [12] and forms precipitate in alkaline media [13]. This is sometimes a barrier for using this material in various useful purposes like as an adsorbent, as packaging material, and so on.…”

Section: Resultsmentioning

confidence: 99%

“…In CHT molecule, the amino sites are the main reactive groups for metals ions, although hydroxyl groups (especially in the C 3 position) may contribute to the sorption process [11]. One of the limitations of CHT is that it is soluble in 2 International Journal of Polymer Science dilute aqueous acidic solution (pH < 6.5), which can convert glucosamine units into soluble form (R-NH 3 + ) [12] and it also gets precipitated in alkaline solution [13]. Another limitation of CHT as an adsorbent is lower thermal stability.…”

Section: Introductionmentioning

confidence: 99%

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Facile Preparation of Biocomposite from Prawn Shell Derived Chitosan and Kaolinite-Rich Locally Available Clay

Biswas

Rashid

Mallik

et al. 2017

International Journal of Polymer Science

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A novel composite material was prepared from prawn shell derived chitosan (CHT) and locally available kaolinite-rich modified Bijoypur clay (MC) using a facile technique in which dilute acetic acid was used as a solvent for dissolving chitosan and composite fabrication whereas distilled water was used for preparing the clay dispersion. Bijoypur clay mainly consists of kaolinite clay mineral and it was modified with the dodecyl amine to make it organophilic. Morphology and properties of the composites (different weight ratio of MC and CHT) have been studied and compared with those of pure CHT and MC. Purification and modification of Bijoypur clay were investigated by X-ray diffraction (XRD), X-ray fluorescence (XRF), and Fourier transformed infrared spectroscopy (FTIR) analyses. The fabrication of CHT-MC composites was confirmed by FTIR analysis. Thermogravimetric analysis (TGA) and differential scanning colorimetry (DSC) were used to investigate the thermal stability of the composites. It was observed that dispersed clay improves the thermal stability and enhances the hardness of the matrix systematically with the increase of clay loading. In this study, a better insolubility in both acidic and alkaline media of the composites is also observed compared to pure chitosan.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Facile Preparation of Biocomposite from Prawn Shell Derived Chitosan and Kaolinite-Rich Locally Available Clay

Biswas

Rashid

Mallik

et al. 2017

International Journal of Polymer Science

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“…It is well known that chitosan is soluble at low pH values of less than 6 (Qin et al, 2006), accordingly low pH values may be detrimental to the modified chitosan bentonite adsorbent. Therefore, it is important to use the modified chitosan bentonite absorbents under relatively elevated pH equal or more than 6.…”

Section: Resultsmentioning

confidence: 99%

Exploratory study to assess the impact of chitosan /bentonite ratio on the metal removal capacity of chitosan modified bentonite clay

2016

Global NEST Journal

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Adsorption is one of the methods that can be used for metal removal. In this study five metals were used cadmium, chromium, lead, copper and nickel (Cd, Cr, Pb, Cu, and Ni) over a concentration range from 0.8 to about 7 mg l -1 for each metal. Adsorbents were prepared with increasing chitosan to bentonite ratio from 0 to 0.67 g chitosan/g bentonite. The study showed that adsorption of metals on plain bentonite and chitosan modified bentonite can fit well with Langmuir and Freundlich adsorption isotherms. Furthermore, the bentonite adsorption capacity will decrease with the increase of chitosan/bentonite ratio. This study concluded that bentonite is a good adsorbent. However, the applicability of bentonite as potential adsorbent may be limited by its physical properties such as slow settling rate and difficulty to use it as an adsorbent in adsorption columns. Despite the decrease of maximum theoretical adsorption capacity as a result of chitosan modification, the addition of small amount of chitosan can improve the physical characteristics of bentonite clay to be used as an adsorbent.

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“…Chitosan is an amino polysaccharide with antifungal effects derived from chitin by alkaline deacetylation. Chitin is the second most abundant polymer in nature after cellulose (25)(26)(27)(28)(29)(30) and has a safe biological profile for patients. It exhibits a therapeutic effect on diabetes along with cholesterol-lowering, woundhealing, antitumor, antifungal, and antimicrobial effects (31,32).…”

Section: Discussionmentioning

confidence: 99%

<i>In vivo</i> study of antifungal effects of low-molecular-weight chitosan against <i>Candida albicans </i>

Atai

Amini

et al. 2017

Journal of Oral Science

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This study investigated the antifungal effects of low-molecular-weight chitosan solution onCandida albicans in denture stomatitis in comparison with nystatin suspension. This randomized, singleblind clinical trial included 40 patients diagnosed with denture stomatitis. Patients were divided into two groups, wherein one was treated with chitosan and the other with nystatin for 2 weeks. Changes in the erythematous area were recorded during and after treatment. A palatal smear was obtained for each patient before and after treatment to determine the number of blastospores and mycelia of C. albicans. The results were compared using the MannWhitney U test, revealing that the chitosan solution significantly decreased the erythematous surface area, burning sensation, time required for clinical improvement, and number of blastospores and mycelia. The antifungal efficacy of chitosan along with its inherent biocompatibility makes it a promising candidate for use as an antifungal mouthwash.

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Water-solubility of chitosan and its antimicrobial activity

Cited by 593 publications

References 36 publications

Facile Preparation of Biocomposite from Prawn Shell Derived Chitosan and Kaolinite-Rich Locally Available Clay

Facile Preparation of Biocomposite from Prawn Shell Derived Chitosan and Kaolinite-Rich Locally Available Clay

Exploratory study to assess the impact of chitosan /bentonite ratio on the metal removal capacity of chitosan modified bentonite clay

<i>In vivo</i> study of antifungal effects of low-molecular-weight chitosan against <i>Candida albicans </i>

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