Water lecithin binding in lecithin-water lamellar phases at 20°C

Modeling Magnetization Transfer Using a Three-Pool Model and Physically Meaningful Constraints on the Fitting Parameters

“…A starting point to modeling magnetization transfer data is to establish reasonable approximations and constraints to the parameters in Eqs. [7,8], [11], and [A1] consistent with experimental MT results and which leave the dimensions of the undetermined parameter space relatively small. The coupling constants and relaxation parameters are all dependent on dynamics within the hydrated systems and therefore will be sensitive to temperature.…”

“…[11], and three-pool model without, Eqs. [7,8], and with exchange effects on the x-and y-components of the bulk and intermediate magnetizations, Eq.…”

“…[8] is well approximated by the results of the two-pool model in Eq. [11]. As expected for a series coupled system, the coupling constant from the reduced three-pool model, κ AC , will be limited by the smaller of the rate constants, κ AB ex and κ…”

“…For hydrogen bonds, E a may be up to 40 kJ (mol Hbond) −1 and will be smaller for fixed dipole-dipole interactions. There is evidence for long-lived water molecules in restricted sites of proteins and lipid bilayers with solvent exchange rates on the order of 10 4 -10 6 s −1 (11,18,59,63).…”

Conformational Analysis of Hexagonal Arrangements of Phosphatidylchloline Head Groups with Bound Waters by Molecular Mechanics.

“…It is also known that several water molecules are bound to the phosphate group in the head group with a lifetime much greater than the reorientation correlation time of the head group [2]. These facts have suggested that hydrated water molecules may be kept tightly bound to the head group while it is rotating.…”