Water‐compatible imprinted polymers based on CS@SiO₂ particles for selective recognition of naringin

Abstract

Molecularly imprinted polymers are being proposed for the development of novel biorecognition elements for active components. In this study, an imprinted chitosan coated silica nanoparticles (I-CS@SiO 2 ) polymer was prepared by a simple procedure, in which, naringin (NG) with antioxidant activity, acted as a template, silica as a matrix and CS as a functional polymer. The binding properties were discussed by the equilibrium binding experiment method. Experiments show that the adsorption characteristics of I-CS@SiO 2 are better than that of nonimprinted polymer. It exhibited high selectivity for NG when compared with the nonimprinted polymer, with an imprinting factor a of 1.74. Scatchard analysis of the I-CS@SiO 2 indicated that there was a class of binding sites during the I-CS@SiO 2 recognizing NG: The dissociation constant of K D is 0.016 mmol L 21 , the maximum apparent binding capacity of B max is 6.56 lmol g 21 .

Water-compatible surface imprinting of ‘Saccharin sodium’ on silica surface for selective recognition and detection in aqueous solution

“…They find the synthetic compounds have good adsorption capacity in water. A lot of people have also used different methods to synthesize molecularly imprinted polymers in aqueous solution successfully [5][6][7][8][9][10][11]. Except the incompatibility issues of water, there is still a big problem -the elution of template molecules, because of the hydrogen bond interaction between template and functional monomer will have effect on the elution of template molecules [12][13][14][15].…”

Oriented, molecularly imprinted cavities with dual binding sites for highly sensitive and selective recognition of cortisol

“…Several cortisol-imprinted polymers have been previously reported [14,15]. They were typically prepared using a single functional monomer because plural binding sites in an imprinted cavity appeared to indicate more sensitive and selective binding activity towards target molecules such as nucleobases [16,17], endocrine desolators [18], herbicides [19], antibiotics [20,21], proteins [22][23][24][25][26], glycans [27][28][29], organic pollutants [30,31] and enzyme inhibitors [32,33]. We have reported cortisol-MIPs prepared with the ability to recognize cortisol using cortisol-21-monomethacrylate and itaconic acid as the template molecule and functional monomer, respectively.…”