Wandering Pneumonia Caused by Dabigatran

Abstract

We herein describe the case of a 74-year-old man who experienced pulmonary consolidation and chest pain following administration of dabigatran, a novel oral anticoagulant. The consolidation settled spontaneously in another lung area, a condition sometimes referred to as "wandering pneumonia." Although we did not find specific pathological evidence of interstitial lung disease on transbronchial lung biopsy, a lung opacity spontaneously disappeared following discontinuance of dabigatran, and there was no recurrence. There are no other reports of dabigatran-induced lung injury, except alveolar hemorrhage and eosinophilic pneumonia. We should consider that any novel drug could cause various types of pulmonary injuries.

Interstitial pneumonia caused by dabigatran

“…Dabigatran is preferred to warfarin in many cases because it offers similar efficacy with a lower risk for bleeding and does not require frequent blood tests [2] . However, few cases of alveolar hemorrhage [3] , [4] , eosinophilic pneumonia [5] , and OP [6] have been reported as adverse events. In the present case, the patient had no symptoms or findings of alveolar hemorrhage.…”

Lipoid pneumonia with neuroendocrine tumorlet: a case report

“…It can present with symptoms such as cough, fever, breathlessness, chest pain, but it can sometimes be asymptomatic. 1,2 It is important to exclude a lung cancer. 2…”