Wall shear stress variations in a 90-degree bifurcation in 3D pulsating flows

Wall shear stress variations and unsteadiness of pulsatile blood-like flows in 90-degree bifurcations

“…not symmetric relative to the peak [24]. However, a welldefined temporal inflow profile is needed in order to determine the periodic pulsating character of the flow and its frequency (Womersley number) response [20,21,48]. As argued for the choice of geometry, regarding uncertainty, it is more important that the inflow profile be reproduce-able in repeated numerical experiments…”

“…In order to focus on the basic properties of the pulsatile flow, a simplified three-dimensional arterial bifurcation model is used [21]. The geometry is believed to be adequate to facilitate the understanding of certain properties of the flow characteristics due to the repeatability of the flow.…”

“…The geometric dimensions of the bifurcation shown in Figs. 2(a) and 4 are D¼13.2 mm and d¼9.35 mm [21]. The 90-degree bifurcation has a smooth, artery like shape with an approximate radius of curvature of 9.7 mm.…”

“…To the knowledge of the authors, this is the first numerical study of its kind considering coupling of the local RBC volume fraction variation affecting the viscosity of the blood flow in large arteries. This study is based upon a geometry used in a previous Newtonian flow study to which comparison can directly be made [21].…”

Heart Valve Tissue Engineering: A Study of Time Varying Effects and Sample Geometry

“…Specifically, OSS has been shown to influence BMSCs proliferation and upregulate transcription factors responsible for phenotypic regulation [52,[56][57][58][59]. In particular, Li et al [53] reported that OSS caused triggering of intracellular calcium mobilization in BMSCs and regulation of osteogenic gene expression.…”