Vulvovaginal–gingival syndrome of lichen planus: Diagnostic and therapeutic challenge

Gökdemir, Gonca; Baksu, Alparslan; Taşkin, Mehtap; Göker, Nimet

doi:10.1046/j.0004-8666.2003.00119.x

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Vulvovaginal Gingival Syndrome and Coeliac Disease2

Clinical Variants1

Complications1

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2005

2018

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Cited by 7 publications

(6 citation statements)

References 14 publications

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“…This unique constellation of genital and mucosal LP is called the vulvovaginalgingival syndrome or plurimucosal LP. 9 Lesions affecting different mucosal sites do not necessarily appear contemporaneously.…”

Section: Clinical Variantsmentioning

confidence: 99%

Vulvar Lichen Planus

Goldstein¹,

Metz²

2005

Clinical Obstetrics and Gynecology

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Section: Clinical Variantsmentioning

confidence: 99%

Vulvar Lichen Planus

Goldstein¹,

Metz²

2005

Clinical Obstetrics and Gynecology

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“…Genital lesions usually cause burning, pain, pruritus and bleeding. Some patients complain of dyspareunia and seropurulent discharge 4,6,7 . Our patient also presented lesions in perianal region, which may happen in the syndrome 2,5 .…”

mentioning

confidence: 49%

“…Some patients complain of dyspareunia and seropurulent discharge. 4,6,7 Our patient also presented lesions in perianal region, which may happen in the syndrome. 2,5 The best way of treating VVGS is not established yet.…”

Section: Vulvovaginal Gingival Syndrome and Coeliac Diseasementioning

confidence: 82%

See 1 more Smart Citation

Vulvovaginal gingival syndrome and coeliac disease

Lima

Werner

Mukai

et al. 2008

Acad Dermatol Venereol

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“…Accurate diagnosis and follow-up of any vulvar lesion is important, particularly when symptoms of vulvovaginitis are persistent [27].…”

Section: Complicationsmentioning

confidence: 99%

A Review of Vulvovaginal-Gingival Syndrome. Case Report

Grau¹,

Roig²,

Juncadella³

et al. 2017

UCMS

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Abstract:Vulvovaginal-gingival syndrome (VVGS) is a chronic mucocutaneous disease of unknown etiology, which consists of a triad of symptoms: vulvar, vaginal and gingival of lichen planus (LP) lesions. The evidence suggests an autoimmune response, a genetic and probably hormonal component. Associated factors observed in LP include stress/anxiety, hepatitis C virus (HCV) and autoimmune diseases, among others. The most serious complication of oral and possibly also vulvar Lichen Planus is the development of squamous cell carcinoma. Corticosteroids are the mainstay treatment for LP in order to control inflammatory activity. In case of failure, immunosuppressive agents can be used (Tacrolimus and Cyclosporine). We present an illustrated case of VVGS who over the years developed tongue cancer and, 10 years later, a vulvar cancer. Oral Lichen Planus (OLP) should be referred to the appropriate specialists to rule out involvement of other mucous membranes and track it early to diagnose a possible malignant transformation. The efficient management of VVGS involves a multidisciplinary approach involving gynecologists, dermatologists and stomatologists.

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Vulvovaginal–gingival syndrome of lichen planus: Diagnostic and therapeutic challenge

Cited by 7 publications

References 14 publications

Vulvar Lichen Planus

Vulvar Lichen Planus

Vulvovaginal gingival syndrome and coeliac disease

A Review of Vulvovaginal-Gingival Syndrome. Case Report

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