Vulvar Lichen Planus

Goldstein, Andrew T.; Metz, Arielle

doi:10.1097/01.grf.0000179670.98939.b7

Cited by 40 publications

(38 citation statements)

References 20 publications

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“…In addition, in erosive lichen planus, the vaginal adhesions are recurrent and unresponsive to therapy such as adhesiolysis and topical estrogen or steroid creams or ointments. 3 Although mild lichen planus cannot be excluded, it is improbable that a mild form of disease would result in vaginal synechiae. Saline microscopy findings were suggestive of atrophic vaginitis without any evidence of infectious pathology such as candidiasis, bacterial vaginosis, or trichomoniasis.…”

Section: Discussionmentioning

confidence: 99%

Severe atrophic vaginitis causing vaginal synechiae and hematocolpos at menopause

Segal

Harvie²,

Siegelman³

et al. 2011

Menopause

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Section: Discussionmentioning

confidence: 99%

Severe atrophic vaginitis causing vaginal synechiae and hematocolpos at menopause

Segal

Harvie²,

Siegelman³

et al. 2011

Menopause

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“…Genital LP commonly affects the vulva, the vagina as well as the glans penis and presents as erosive LP [63,64]. Without treatment it can lead to scarring and disfigurement.…”

Section: Discussionmentioning

confidence: 99%

Oral, Esophageal and Cutaneous Lichen Ruber Planus Controlled with Alitretinoin: Case Report and Review of the Literature

Kolios¹,

Maggio²,

Gubler

et al. 2013

Dermatology

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Background: Therapy-resistant lichen planus (LP) can be a challenging condition for dermatologists. There are some case reports about successful treatments with alitretinoin of cutaneous and oral, but not of esophageal LP. Objective: We present the unique case of a patient with cutaneous, oral and esophageal LP which was refractory to classical treatment options (topical clobetasol propionate and pimecrolimus, intramuscular triamcinolone acetonide); because of systemic side effects the patient did not tolerate systemic acitretin dosed up to 25 mg daily. Methods: Oral alitretinoin was used at a dose of 30 mg daily. Results: Both oral and skin changes as well as dysphagia completely resolved within 4 weeks without any severe side effects and the drug was used for 6 months. No papules, intraoral striae or dysphagia recurred during the 6 months of treatment. After 4 months the patient relapsed with mucosal patches so that a second cycle was initiated for 6 months where oral LP lesions resolved after 4 weeks also (with sporadic mild headache). Conclusion: Further studies are needed to better understand the impact of alitretinoin in LP. Our observation suggests alitretinoin as a new, well-tolerated treatment option for esophageal LP after failed response to conventional treatments.

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“…Inflammatory Vulvar Dermatoses 467erosive form of vulvar LP commonly present with vulvar pain, dyspareunia, and dysuria, whereas women with the nonerosive vulvar form commonly present with severe itch 7,8. Patients with vaginal LP may present with copious yellow to yellowgreen vaginal discharge, due to a desquamative vaginitis.…”

mentioning

confidence: 98%

“…LP similar to LS can be also associated with other autoimmune diseases, such as vitiligo, pernicious anemia, alopecia areata, and thyroid disease 8. It is clinically important to note that erosive LP of the vulvovaginal tissue is most commonly associated with oral erosive disease, termed the vulvovaginal gingival syndrome, thus necessitating an oropharyngeal examination in all patients with genital LP 7. Oropharyngeal involvement may reveal Wickham striae on the buccal mucosa, erosions of the marginal gingiva, atrophic papillae on the tongue's surface, or erosions on the tongue(Figs.…”

mentioning

confidence: 98%

Inflammatory Vulvar Dermatoses

Guerrero

Venkatesan

2015

Clinical Obstetrics &Amp; Gynecology

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Inflammatory vulvar dermatoses affect many women, but are likely underdiagnosed due to embarrassment and reluctance to visit a health care provider. Although itch and pain are common presenting symptoms, the physical examination can help distinguish between different disease entities. Because many women's health providers have minimal training in the categorization and management of dermatologic disease, definitive diagnosis and management can be difficult. Herein, strategies for diagnosing vulvar lichen sclerosus, lichen planus, contact dermatitis, lichen simplex chronicus, and psoriasis are discussed along with basic management of these diseases, which commonly involves decreasing inflammation through behavioral change, gentle skin care, topical corticosteroids, and systemic therapies.

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Vulvar Lichen Planus

Cited by 40 publications

References 20 publications

Severe atrophic vaginitis causing vaginal synechiae and hematocolpos at menopause

Severe atrophic vaginitis causing vaginal synechiae and hematocolpos at menopause

Oral, Esophageal and Cutaneous Lichen Ruber Planus Controlled with Alitretinoin: Case Report and Review of the Literature

Inflammatory Vulvar Dermatoses

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