Vulvar Syringoma: A Rare Cause of Vulvar Pruritus

Ruíz‐González, Inmaculada; Delgado, Saul Muñoz; Alonso, T.; Ingelmo, José María Rodríguez

doi:10.1016/s1578-2190(08)70323-8

Cited by 5 publications

(4 citation statements)

References 10 publications

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“…Three kinds of clinical manifestations have been documented: 1) multiple flesh-coloured or brownish papules with symmetrical involvement of the labia majora, 2) cystic lesions or 3) lichenoid plaques ( 11 , 12 , 18 , 19 ).…”

Section: Introductionmentioning

confidence: 99%

An Unusual Case of Genital Lesion: A Vulvar Syringoma

Algeri¹,

Rodella²,

Manfredini³

et al. 2021

JFRH

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Objective: Syringoma is a benign adnexal neoplasm of sweat gland, usually presenting as extra-genital lesions, while vulvar localization is rare. Moreover, syringoma is an uncommon vulvar neoplasms. Case report: A 44-year-old woman with previous diagnosis of duodenal gastrointestinal stromal tumour, underwent a local surgical excision for an isolated, painful, vulvar lesion. The specimen was submitted for histological examination. A vulvar syringoma was diagnosed. Conclusion: We describe this case according on its rarity and atypical presentation as well; therefore, vulvar neoplasms encompass many differential diagnoses, among which the incidence rate of syringoma is very low. Although its rarity, syringoma should be included among the differential diagnosis for vulvar neoplasm.

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Section: Introductionmentioning

confidence: 99%

An Unusual Case of Genital Lesion: A Vulvar Syringoma

Algeri¹,

Rodella²,

Manfredini³

et al. 2021

JFRH

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“…The most common presentation is that of multiple flesh-coloured or brownish papules located symmetrically on the labia majora. Cystic lesions or lichen planus-like plaques may also be present [5]. Cutaneous mastocytosis, fibrofolliculomas, velus hair cysts, steatocystoma multiplex, Fox-Fordyce disease, lichen simplex and lichen planus should be considered in the differential diagnosis [6].…”

Section: Discussionmentioning

confidence: 99%

Vulvar syringomas — an underrecognized condition

Kołcz,

Kaznowska,

Reich

et al. 2024

Forum Dermatologicum

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Syringoma is a benign neoplasm originating from the eccrine ducts of the sweat gland. Lesions are most commonly located on the face. Rarely, do syringomas develop in the vulvar region, where they may be accompanied by persistent pruritus. The article presents the case of a 34-year-old female patient, in whom small nodules and pruritus of the vulva had persisted for approximately two years. The paper includes a description of the dermoscopic features of the skin lesions. The final diagnosis was made based on the histopathological examination. The paper also discusses the most used therapeutic methods in this rare entity.

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“…Vulvar syringomas can be presented in three different clinical forms. These are multiple skin‐colored or brownish papules with symmetrical involvement of the labia majora, cystic lesions, or lichenoid plaques 6,7 . Lichen planus, Fox‐Fordyce disease, lichen simplex chronicus, steatocystoma multiplex, anogenital wart, and epidermal cysts should be considered in differential diagnosis 4,8,9 …”

Section: Discussionmentioning

confidence: 99%

“…lesions, or lichenoid plaques. 6,7 Lichen planus, Fox-Fordyce disease, lichen simplex chronicus, steatocystoma multiplex, anogenital wart, and epidermal cysts should be considered in differential diagnosis. 4,8,9 No treatment is required in syringomas except for cosmetic concerns.…”

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confidence: 99%

An alternative for the treatment of vulvar syringoma: 577 nm pro‐yellow laser

Saraç

Önder

2021

J of Cosmetic Dermatology

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Syringoma that characterized by skin-colored 1-5 mm in diameter papules is a benign sweat gland tumor. 1 It predominantly appears in females during puberty and the lesions are frequently located in eyelids, malar regions, neck, and chest. 2 Vulvar syringoma is an extremely rare condition that was firstly described by Carneiro et al in 1971. 3 Although most of the vulvar syringomas asymptomatic, it may rarely present with vulvar pruritus. 4 There are various treatment choices for the management of vulvar syringomas including topical tretinoin, chemical peelings, electrodessication, laser therapy, and surgical excision. 5 Here, we present a case with vulvar syringoma that was treated by 577 nm pro-yellow laser. | C A S E REP ORTA 42-year-old woman was admitted to our dermatology clinic with a history of multiple skin-colored slightly elevated tumors located on vulva and vulvar itching. The lesions have been present since the age of 18 and number of the lesions increased over the years. Vulvar pruritus was intermittent and there was no change in symptoms during menstruation. On physical examination; multiple, soft, skin-colored, 2-5 mm-diameter papules were seen on the vulva.No similar lesions were present elsewhere. A biopsy of the lesion was performed. Histopathological examination revealed numerous small ducts lined by a double layer of epithelial cells embedded in a fibrous stroma. Some of the ducts contained amorphous debris in the lumina. The diagnosis of vulvar syringoma was made on the basis of these clinical and histopathological findings. The lesions were treated with 577 nm pro-yellow laser after the application of local anesthesia. We used continuous wave mode and only two sessions were applied with 4 weeks intervals. After the procedure, the patient was recommended to use antibiotic cream that contains fusidic acid. After 4 weeks of follow-up, the lesions almost completely disappeared with no complaints of pruritus (Figures 1 and 2). | DISCUSS IONSyringoma is a benign tumor of the eccrine sweat glands that presented with multiple skin-colored tiny papules located on eyelids, cheeks, neck, chest, and rarely on vulva 2 The lesions are usually asymptomatic but in vulvar syringoma pruritus and discomfort may be experienced during menstruation, pregnancy, and summer months. 6 Vulvar syringomas can be presented in three different clinical forms. These are multiple skin-colored or brownish papules with symmetrical involvement of the labia majora, cystic

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Vulvar Syringoma: A Rare Cause of Vulvar Pruritus

Cited by 5 publications

References 10 publications

An Unusual Case of Genital Lesion: A Vulvar Syringoma

An Unusual Case of Genital Lesion: A Vulvar Syringoma

Vulvar syringomas — an underrecognized condition

An alternative for the treatment of vulvar syringoma: 577 nm pro‐yellow laser

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