von Willebrand Disease in the Pediatric and Adolescent Population

Mikhail, Sameh; Kouides, Peter A.

doi:10.1016/j.jpag.2010.08.005

Cited by 32 publications

(25 citation statements)

References 76 publications

(22 reference statements)

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“…It is a significant cause of abnormal uterine bleeding with prevalence ranging from 3 to 44% in various studies. 23,24,25 Coagulopathy accounted for 2.42% cases of AUB in our study. VWD and platelet dysfunction are the commonest hemostatic abnormalities which are seen in adolescents with AUB 26,27,28 However we did not encounter any such case.…”

Section: Fig 1 Study Flow Chartmentioning

confidence: 46%

Study of Adolescent Abnormal Uterine Bleeding (Aub) and Its Outcome - In Tertiary Centre K.I.M.S. Karad

Laddad¹,

Kshirsagar²,

Patil³

et al. 2015

jemds

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BACKGROUND/AIMS:Menstruation is a normal part of adolescence, but for girls with excessive uterine bleeding, it can be associated with significant morbidity. Menstrual disorders and abnormal uterine bleeding (AUB) are among the most frequent gynaecological complaints of adolescents. AUB has been defined in the past by a variety of terms and there have been inconsistencies and lack of categorization of various potential causes of AUB. To have standard nomenclature internationally, palm coein Classification of AUB was introduced in 2011 by FIGO Menstrual disorder group for non-pregnant, reproductive age women. In the present study we aimed to evaluate cases of adolescent AUB by investigations and palm coein approach. METHODS: The study was conducted prospectively on all adolescent girls attending OPD at Krishna institute of medical sciences Karad, Menstrual complaints were classified according to palm coein approach after a thorough history taking, examination and investigations. RESULTS: Prevalence of menstrual disorders in adolescents was 64.5%, of which 86.90% were attributed to AUB. Palm coein approach was applied to AUB cases. Ovulatory disorders (AUB-0) formed a major chunk of adolescent AUB (96.90%), of which 60.60% were due to immaturity of Hypothalamic Pituitary Ovarian axis, 27.87% due to polycystic ovarian syndrome and 8.48% due to Thyroid disorders. Contribution of coagulopathy to AUB was 2.42%. Polyps and leiomyoma were seen in 1.2% and 0.6% of cases respectively. All cases were classified when palm coein was applied. CONCLUSION: AUB in adolescents can also be classified by palm coein to standardize nomenclature and abandonment of terms like menorrhagia, metrorrhagia and dysfunctional uterine bleeding and treated it successfully.

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Section: Fig 1 Study Flow Chartmentioning

confidence: 46%

Study of Adolescent Abnormal Uterine Bleeding (Aub) and Its Outcome - In Tertiary Centre K.I.M.S. Karad

Laddad¹,

Kshirsagar²,

Patil³

et al. 2015

jemds

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show abstract

“…4 Menorrhagia is the most common presenting symptom in women with bleeding disorders, ranging from 3% to 36% in adolescent with VWD. 6 Medications that increase the risk of bleeding such as heparin, aspirin, NSAIDs, and those that affect platelet function should generally be avoided in patients with bleeding disorders. 7 Treatment of VWD usually includes desmopressin and/or an antifibrinolytic agent such as tranexamic acid or aminocaproic acid for mild to moderate bleeding and von Willebrand factor replacement for more severe bleeding episodes.…”

Section: Discussionmentioning

confidence: 99%

“…Hormone therapy is often used as first line or adjunct therapy to other hematologic agents. 6 Estrogen containing hormonal regimens along with antifibrinolytics increase Fig. 1.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic Pulmonary Hypertension Causing Acquired von Willebrand Disease and Menorrhagia

Sokkary

Dietrich

Venkateswaran

2011

Journal of Pediatric and Adolescent Gynecology

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“…Anormal uterin kanamaya yol açan en sık hematolojik hastalık von Willebrand hastalığıdır. Her ne kadar genel popülasyonda görülme sıklığı düşük olsa da (%1), anormal uterin kanaması olan adolesanlarda prevalans % 3-36 arasında bildirilmektedir (8,9) . Genel koagülasyon bozuklukları da ikinci en sık nedeni oluşturmaktadır.…”

Section: öYküunclassified

Gynecologic Approach to Abnormal Uterine Bleeding in Adolescents

Yaşa¹,

Dural²

2016

Cocuk Dergisi

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von Willebrand Disease in the Pediatric and Adolescent Population

Cited by 32 publications

References 76 publications

Study of Adolescent Abnormal Uterine Bleeding (Aub) and Its Outcome - In Tertiary Centre K.I.M.S. Karad

Study of Adolescent Abnormal Uterine Bleeding (Aub) and Its Outcome - In Tertiary Centre K.I.M.S. Karad

Idiopathic Pulmonary Hypertension Causing Acquired von Willebrand Disease and Menorrhagia

Gynecologic Approach to Abnormal Uterine Bleeding in Adolescents

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