Volumetric Properties, Viscosity, and Refractive Indices of Different Naringenin Solutions at Several Temperatures

Abstract

Thermophysical properties including densities and viscosities of naringenin in aqueous solutions of ethanol/1-propanol with alcohol concentrations of (24.00 to 40.00) mol•kg −1 have been measured as a function of concentration of naringenin at temperatures from (293.15 to 323.15) K and atmospheric pressure. Also, refractive indices for studied systems have been determined at 298.15 K. The measured data were used to calculate the apparent molar volume (V ϕ ), standard partial molar volume (V ϕ 0 ), partial molar volume (V̅ ), viscosity B-coefficients, and molar refractions (R m ). The viscosity and refractive index data have been analyzed by Jones−Dole and Lorentz−Lorenz equations, respectively. The trends of variation of experimental and calculated parameters have been discussed according to the interactions between solvents and solute. The obtained results imply that naringenin acts as a structure maker in the studied system.

Study on the Interactions of a Promising Cancer-Preventive Drug Ferulic Acid in Aqueous Ethanol/1-Propanol Solutions Using Volumetric, Viscometric, and Refractive Index Approaches

“…hydrophilic–hydrophobic interactions between the hydroxyl, carboxyl, and ether groups of the FA molecule and the alkyl group of the ethanol and 1-propanol molecules (negative contribution to volume); , …”

“…Fourth, from Table , it can also be observed that the V ϕ0 values for FA decrease as the temperature of the aqueous ethanol/1-propanol solutions is raised. This may be due to the decrease in hydrophobic hydration at higher temperatures , and a release of a fraction of water molecules from the hydrophobic hydration layer, which leads to a negative contribution to V ϕ0 . A similar result was also observed by Ayranci et al for FA in methanol and by Yan et al for naringenin in an aqueous ethanol/1-propanol solution.…”

“…70 This effect of hydrogen bond strengthening weakens the hydrophobic effect of FA and finally leads to the increase in V ϕ0 . A similar result was observed by Yan et al for naringenin 42 and by our group for 7-hydroxy-4-methylcoumarin 31 and 7-hydroxycoumarin 34 in the aqueous ethanol/1propanol solutions. Third, the data presented in Table 4, Figures 1 and S1 show that in the aqueous ethanol/propanol solutions the V ϕ0 of FA first increases and then decreases with increasing the total molarity of the alcohols m alcohol in solutions, with the maximum V ϕ0 value in aqueous ethanol and 1-propanol solutions being 18 and 20 mol•kg −1 , respectively.…”

“…31 Thus, the maximum V ϕ0 value corresponds to a higher concentration of 1-propanol. Similar results were observed by Yan et al for naringenin 42 and our group for 7-Hydroxy-4-methylcoumarin 31 and 7-hydroxycoumarin 34 in the aqueous ethanol/1-propanol solutions.…”

“…This reveals that the overall polarizability of FA in aqueous alcohol solution increases with increasing the concentration of FA, 37 which may explain the observed dependences of ρ and η on m FA . Similar results were observed by Ali et al 81 for glycine in aqueous solutions of diols and Yan et al 42 for naringenin in aqueous ethanol/1-propanol solutions. In addition, for the same m alcohol values, R D of FA in the aqueous 1-propanol ternary mixtures is greater than that in the aqueous ethanol ternary mixtures.…”