Volatile and Non-Volatile Chemical Compounds and Biological Power of the genus Lavandula: Case of two Moroccan Lavenders Lavandula angustifolia Mill. (Cultivated Lavander) and Lavandula pedunculata (Mill.) Cav. (Spontaneous Lavander)

Radi, Fatima Zahrae; Zekri, Nadia; Drioiche, Aziz; Zerkani, Hannou; Boutakiout, A.; Bouzoubaa, Amal; Zair, Touriya

doi:10.21608/ejchem.2021.82036.4053

Cited by 1 publication

(3 citation statements)

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“…Likewise, linaool acetate, a primary constituent of L. abrialis EO, has a very substantial correlation with strain growth inhibition of E. cloacae and S. aureus. These results corroborate with previous studies including Radi et al (2022) who showed that L. stoechas EOs demonstrated significant antibacterial activity against several strains, such as S. aureus, Staphylococcus typhi, E. coli, A. baumanii, E. Cloacae and Staphylococcus dysenteria and antifungal activity against Candida glabrata, Candida albicans, Candida spp., Aspergillus fisheri, and Fusarum solani. According to Dorman and Deans, (2000), the antibacterial activity was brought on by the presence of phenol (1,8 cineole), alcohols (cubenol, borneol, terpineol, etc.…”

Section: Correlation Between the Chemical Composition Of The Eos Stud...supporting

confidence: 92%

“…Indeed, camphor which is a major compound of the two studied EOs (24.35% for L. stoechas and 11.24% for L. abrialis), presented a strong correlation with the antioxidant activity, which was confirmed by the results of the heat map. Previous studies have confirmed that this compound also has strong antioxidant activity (Radi et al, 2022;Laib, 2012). Additionally, to camphor's particular antioxidant properties, the synergistic interactions that can be established between the different constituents of essential oil were also behind its considerable antioxidant power (Laib and Barkat, 2011;Radi et al, 2022;Laib, 2012;Fatiha et al, 2011).…”

Section: Antioxidant Activity Of Essential Oils By the Dpph Anti-radi...mentioning

confidence: 78%

“…Previous studies have confirmed that this compound also has strong antioxidant activity (Radi et al, 2022;Laib, 2012). Additionally, to camphor's particular antioxidant properties, the synergistic interactions that can be established between the different constituents of essential oil were also behind its considerable antioxidant power (Laib and Barkat, 2011;Radi et al, 2022;Laib, 2012;Fatiha et al, 2011).…”

Section: Antioxidant Activity Of Essential Oils By the Dpph Anti-radi...mentioning

confidence: 78%

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Comparative study of the chemical composition, antioxidant, and antimicrobial activity of the essential oils extracted from Lavandula abrialis and Lavandula stoechas: in vitro and in silico analysis

Radi,

Eddardar,

Drioiche

et al. 2024

Front. Chem.

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This work aims to add value to the Lavandula genus by identifying the chemical composition, antioxidant, and antimicrobial activities of two species lavender from Oulmès in Morocco; Lavandula abrialis and Lavandula stoechas. The uniqueness lies in the integrated approach that combines in vitro and in silico analyses to assess the biological properties of the essential oils (EO). The objective of this study is to enhance the significance of the Lavandula genus by analyzing the chemical composition, antioxidant properties, and antimicrobial effects of two lavender species found in Oulmès, Morocco: Lavandula abrialis and Lavandula stoechas. The distinctiveness is in the comprehensive methodology that merges in vitro and in silico investigations to evaluate the biological characteristics of the essential oils (EO). The extraction of essential oils (EO) by hydrodistillation from the aerial parts of Lavandula abrialis gave a high yield of essential oils (2.9%) compared to Lavandula stoechas (2.3%). A GC-MS analysis of the chemical composition revealed 56 chemical compounds, with some variation in the predominant components, representing between 99.98% and 100% of the EOs of the studied lavenders. Their antioxidant activity was assessed using the DPPH test. This method revealed that L. stoechas EO has a higher percentage of free radical inhibition than L. abrialis. The IC50 values demonstrate that the antioxidant activity of ascorbic acid is higher (1.62 g/mL) than the EOs of tested plants. Noteworthy, the EO of L. stoechas is more potent (12.94 g/mL) than that of Lavandula tibialis (34.71 g/mL). Regrading, the antibacterial tests, the EO of L. abrialis was particularly active against Staphylococcus aureus BLACT, which is inhibited at a concentration of 6.25 g/mL, while L. stoechas EO has a strong effect on Escherichia coli, with a MIC of 1.56 g/mL. Concerning the antifungal activity of the EOs, yeasts showed sensitivity toward EOs extracted from both L. tibialis and L. stoechas. Moreover, an in silico study was conducted targeting sarA protein of S. aureus (PDB ID: 2fnp) and NADPH oxidase from Lavandula sanfranciscensis (PDB: 2CDU) and results showed that Ishwarone and Selina-3,7 (11)-diene exhibited highest binding energy with −9.8 and −10.8 kcal/mol respectively. Therefore, these two compounds could be used as an antibacterial and antioxidant agents however more experimental and molecular study should be required.

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Section: Correlation Between the Chemical Composition Of The Eos Stud...supporting

confidence: 92%

Section: Antioxidant Activity Of Essential Oils By the Dpph Anti-radi...mentioning

confidence: 78%

Section: Antioxidant Activity Of Essential Oils By the Dpph Anti-radi...mentioning

confidence: 78%

See 1 more Smart Citation

Comparative study of the chemical composition, antioxidant, and antimicrobial activity of the essential oils extracted from Lavandula abrialis and Lavandula stoechas: in vitro and in silico analysis

Radi,

Eddardar,

Drioiche

et al. 2024

Front. Chem.

Self Cite

View full text Add to dashboard Cite

show abstract

Volatile and Non-Volatile Chemical Compounds and Biological Power of the genus Lavandula: Case of two Moroccan Lavenders Lavandula angustifolia Mill. (Cultivated Lavander) and Lavandula pedunculata (Mill.) Cav. (Spontaneous Lavander)

Abstract: Volatile and Non-Volatile Chemical Compounds and Biological Power of the genus Lavandula: Case of two Moroccan Lavenders Lavandula angustifolia Mill. (Cultivated Lavender) and Lavandula pedunculata (Mill.) Cav.

Cited by 1 publication

References 27 publications

Comparative study of the chemical composition, antioxidant, and antimicrobial activity of the essential oils extracted from Lavandula abrialis and Lavandula stoechas: in vitro and in silico analysis

Comparative study of the chemical composition, antioxidant, and antimicrobial activity of the essential oils extracted from Lavandula abrialis and Lavandula stoechas: in vitro and in silico analysis

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