Vocal Cord Dysfunction: A Frequently Forgotten Entity

Campainha, Sérgio; Ribeiro, Carmelita; Guimarães, Márcio Freitas; Lima, Ricardo

doi:10.1155/2012/525493

Cited by 7 publications

(5 citation statements)

References 12 publications

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“…Dysphonia and aphonia have also been described between attacks of respiratory distress. 2 Diagnosis of PVCD based on symptoms alone is inaccurate. In an asymptomatic period, physical examination will be normal.…”

Section: Discussionmentioning

confidence: 99%

“…Depending on the history obtained, provocation with stimuli known to induce symptoms as exercise or cold air can increase the diagnostic yield. 2 Optimal management of PVCD requires the identification and management of contributing factors. Short-term symptomatic control includes relaxation techniques such as pursing lips, panting, and relaxing the shoulders.…”

Section: Discussionmentioning

confidence: 99%

“…Depending on the history obtained, provocation with stimuli known to induce symptoms as exercise or cold air can increase the diagnostic yield. 2…”

Section: Discussionmentioning

confidence: 99%

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Hyperventilation-related hyperlactataemia in a case of paroxysmal vocal cord dysfunction

Mohamed¹,

Sturman²

2016

Journal of the Intensive Care Society

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Paroxysmal Vocal Cords Dysfunction(PVCD), also known as paradoxical vocal cord motion, is abnormal adduction of the vocal cords during inspiration. Like asthma, PCVD can be triggered by breathing in lung irritants, upper respiratory infection or exercise. However, unlike asthma, PCVD is not an immune system reaction and does not involve the lower airways. Treatment for the two conditions differs. Plasma lactate levels are usually associated with acidosis and an increased risk of poor outcome and are described in a number of disease states of circulatory and/or respiratory failure. In patients with psychogenic hyperventilation, high lactates are associated with hypocapnia and alkalosis and should not necessarily be considered as an adverse sign. We describe a case of a young patient with PCVD mimicking asthma with high plasma lactate and discuss the mechanisms involved.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Hyperventilation-related hyperlactataemia in a case of paroxysmal vocal cord dysfunction

Mohamed¹,

Sturman²

2016

Journal of the Intensive Care Society

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“…EILO and ILO have only recently been assigned distinct labels, previously having been referred to as vocal cord dysfunction (VCD), paradoxical vocal fold motion (PVFM), fictitious asthma, or laryngeal dysfunction. 20,21,[26][27][28] When left untreated, EILO/ILO symptoms may lead to recurrent hospitalizations, emergency department visits, inability to participate in athletics, inappropriate medication, or even intubation. 7,8,11,29 Although the prevalence of EILO/ILO remains unknown, emerging evidence suggests the condition is relatively common-occurring in as many as 2% to 22% of dyspnea patients.…”

Section: Introductionmentioning

confidence: 99%

Clinical Profiles of Children and Adolescents With Induced Laryngeal Obstruction (ILO) and Exercise Induced Laryngeal Obstruction (EILO)

Fujiki,

Olson-Greb,

Thibeault

2023

Ann Otol Rhinol Laryngol

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Purpose: To compare clinical profiles of pediatric patients with Induced Laryngeal Obstruction (ILO), Exercise Induced Laryngeal Obstruction (EILO), and EILO with non-exertion related secondary triggers (EILO+). Methods: A retrospective observational cohort design was employed. Four-hundred and twenty-three patients <18 years of age were identified from the electronic medical record of a large children’s hospital. All patients underwent evaluations with a laryngologist and speech-language pathologist and were diagnosed with EILO/ILO. Patients were divided into 3 groups based on dyspnea triggers reported in initial evaluations. Groups consisted of patients with EILO (N = 281), ILO (N = 30), and EILO+ (N = 112). Patient demographics, EILO/ILO symptoms, endoscopy findings, medical comorbidities, medical history, and EILO/ILO treatment information were extracted and compared across EILO/ILO subtypes. Results: Patients with EILO experienced higher rates of hyperventilation ( P < .001), sore throat ( P = .023), and chest pain ( P = .003). Patients with ILO were significantly younger in age ( P = .017) and presented with increased rates of nighttime symptoms ( P < .001), globus sensation ( P = .008), self-reported reflux symptoms ( P = .023), and history of gastrointestinal conditions ( P = .034). Patients with EILO+ were more likely to be female ( P = .037) and presented with higher prevalence of anxiety ( P = .003), ADHD ( P = .004), chest tightness ( P = .030), and cough ( P < .001). Conclusions: Patients with EILO, ILO, and EILO+ present with overlapping but unique clinical profiles. A prospective study is warranted to determine the etiology of these differences and clarify how the efficacy of EILO, ILO, and EILO+ treatment can be maximized. Level of Evidence: 4

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“…However, the differential diagnosis includes other disorders that should also be kept in mind, such as vocal cord polyps, vocal cord granulomas, unilateral or bilateral vocal cord paralysis, and vocal cord tumors. 6 …”

Section: Introductionmentioning

confidence: 99%

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

Kashif

Singh

Aslam

et al. 2017

SAGE Open Medical Case Reports

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Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma.

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Vocal Cord Dysfunction: A Frequently Forgotten Entity

Cited by 7 publications

References 12 publications

Hyperventilation-related hyperlactataemia in a case of paroxysmal vocal cord dysfunction

Hyperventilation-related hyperlactataemia in a case of paroxysmal vocal cord dysfunction

Clinical Profiles of Children and Adolescents With Induced Laryngeal Obstruction (ILO) and Exercise Induced Laryngeal Obstruction (EILO)

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

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