Vocal allergy: recent advances in understanding the role of allergy in dysphonia

Abstract

New evidence has highlighted the likelihood that allergies are indeed associated with dysphonia. The existence of a direct allergic response in the larynx has meaningful implications for the diagnosis and treatment of dysphonia. Further research is needed to identify the underlying pathways mediating the laryngeal response to allergy so that improved diagnostic and therapeutic techniques can be developed.

High Prevalence of Laryngopharyngeal Reflux Disease in Patients With Lumbar Kyphosis

“…Because LPR symptoms are nonspecific, various factors such as smoking, neurological disorders, and allergic rhinitis can lead to an overdiagnosis of LPRD or an increased risk of reflux disease. [16][17][18] However, the present study's subjects showed no significant difference in regard to the potential confounding factors.…”

Histological Effects of Inhaled Corticosteroids and ß2‐agonists on Laryngeal Mucosa in an Allergic Rat Model

“…Wistar albino rats (n = 32) were sensitized intraperitoneally on days 0 and 7 with 1 mg ovalbumin (Sigma Aldrich, St. Louis, Missouri) and 200 mg aluminium hydroxide (Al(OH) 3 ) (Merck, Germany). The protocol used widely for the induction of allergic airway involves the use of Al(OH) 3 as adjuvant for the allergen (ovalbumin) in the intraperitoneal phase of sensitization. 23 Eight additional rats served as controls.…”

Comparison of Acoustic and Stroboscopic Findings and Voice Handicap Index between Allergic Rhinitis Patients and Controls

“…After that report, it was estimated that patients with laryngeal pathologies would have difficulty prolonging the voiced sound /z/ for the same length of time as voiceless /s/ in many studies (3). Therefore, the s/z ratio is estimated to be longer then 1.2-1.4 in laryngeal pathologies.…”