In this paper, we present efficient VLSI layouts of several hypercubic networks. We show that an N-node hypercube and an N-node cube-connected cycles (CCC) graph can be laid out in 4N 2 =9 + oN 2 and 4N 2 =9 log 2 2 N + oN 2 = log 2 N areas, respectively, both of which are optimal within a factor of 1:7 + o1. We introduce the multilayer grid model, and present efficient layouts of hypercubes that use more than 2 layers of wires. We derive efficient layouts for butterfly networks, generalized hypercubes, hierarchical swapped networks, and indirect swapped networks, that are optimal within a factor of 1 + o1. We also present efficient layouts for folded hypercubes, reduced hypercubes, recursive hierarchical swapped networks, and enhanced-cubes, which are the best results reported for these networks thus far.